19 Harley St, London, W1G 9QJ, UK
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[Interventions on the intervertebral discs. Indications, techniques and evidence levels]

CLINICAL ISSUE: Over the last decades a number of different minimally invasive interventions have been proposed for the treatment of intervertebral disc herniation and degeneration. All of these interventions aim at relieving pressure from compressed nerve roots by mechanical ablation, chemical dissolution, evaporation or coagulation of disc tissue. STANDARD TREATMENT: Microsurgical sequestrectomy with direct visualization of the spinal canal. TREATMENT INNOVATIONS: Minimally invasive intradiscal interventions, such as chemonucleolysis, manual and automated disc decompression, laser disc decompression, nucleoplasty and thermal anular radiofrequency (RF) techniques with posterolateral access to the intervertebral disc. PERFORMANCE: The effectiveness and safety of the different minimally invasive procedures are compared to the standard surgical procedure on the basis of a literature review. ACHIEVEMENTS: For patients with disc herniation requiring surgery, microsurgical sequestrectomy is the treatment of choice, while discectomy is obsolete. Intradiscal procedures have a low level of evidence while long-term results are still lacking. Randomized controlled trials are required to generate evidence-based results. PRACTICAL RECOMMENDATIONS: Indications for treatment should be established by an interdisciplinary team with the choice of treatment depending on the interventionalist’s expertise and skills. In carefully selected patients scheduled for elective treatment, the different minimally invasive procedures allow adequate treatment when performed by an experienced interventionalist

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The Harley Street Hospital


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The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

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