Interplay of radiation remedy and radiofrequency kyphoplasty within the remedy of myeloma sufferers.
Technol Well being Care. 2017;25(Three):567-575
Authors: Bornemann R, Roessler PP, Jansen TR, Rommelspacher Y, Sander Okay, Wirtz DC, Pflugmacher R, Frey SP
BACKGROUND: 30% of myeloma sufferers undergo from vertebral compression fractures (VCF). Consequently, augmentation typically turns into inevitable to forestall additional issues. This examine evaluated the interplay of radiation remedy (RT) and radiofrequency kyphoplasty (RFK) within the remedy of myeloma related VCF.
METHODS: Eighty-six myeloma sufferers with VCF have been handled with RFK adopted by radiation remedy (RFK group) or vice versa (RT group). Visible analgoue scale (VAS), Oswestry-Incapacity-Index (ODI), vertebral top and kyphosis angle have been assessed preoperatively, Three-Four days, Three and 6 months postoperatively. Antagonistic occasions like cement leakage or extra fractures have been documented.
RESULTS: Each teams achieved comparable outcomes, however the course of VAS and kyphosis angle differed. Early postoperative kyphosis angles improved considerably within the RFK group, however considerably worsened afterwards. The RT group confirmed a development in direction of considerably enchancment postoperatively and minor worsening afterwards. VAS remained fixed within the RT group and worsened within the RFK group after 6 months. Extra cement leakages and extra fractures have been famous within the RT group.
CONCLUSIONS: RFK is an efficient methodology for treating VCF in myeloma sufferers unbiased of remedy order with regard to radiation remedy. Nevertheless, RT ought to be carried out after RFK to reduce dangers of cement extrusion and extra fractures.
PMID: 28009343 [PubMed – indexed for MEDLINE]