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Impact of depression and anxiety on patient reported outcomes measures after lumbar fusion – Lumbar Fusion

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The article investigates the impact of depression and anxiety on patient-reported outcomes following lumbar fusion surgery. The retrospective study included 156 patients, with 25% having depression and/or anxiety. While baseline disability and quality of life scores were worse in the depression and anxiety group, both cohorts showed similar improvement in outcomes at the two-year follow-up. The study concludes that patients with anxiety and depression are no less likely to benefit from appropriately planned lumbar fusion surgery

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
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Published article

: The present study showed similar improvement in PROMs following lumbar fusion for patients with anxiety and depression compared to healthy controls. These data suggest these patients are no less likely to benefit from appropriately planned lumbar fusion.

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World Neurosurg. 2024 Apr 2:S1878-8750(24)00534-5. doi: 10.1016/j.wneu.2024.03.148. Online ahead of print. ABSTRACT INTRODUCTION: Depression and anxiety are common in patients undergoing spinal surgery and might negatively impact outcomes. This study investigates the possible effect of these diagnoses on patient reported outcomes following lumbar fusion. METHODS: Retrospective review of a registry containing prospectively collected data of,

World Neurosurg. 2024 Apr 2:S1878-8750(24)00534-5. doi: 10.1016/j.wneu.2024.03.148. Online ahead of print.

ABSTRACT

INTRODUCTION: Depression and anxiety are common in patients undergoing spinal surgery and might negatively impact outcomes. This study investigates the possible effect of these diagnoses on patient reported outcomes following lumbar fusion.

METHODS: Retrospective review of a registry containing prospectively collected data of lumbar fusion procedures at a single institution was performed from 5/23/2012 to 6/15/2022. Patients with a minimum of two year follow up were included. Demographic information, diagnoses,medications, patient-reported outcomes measures (PROMs), and complications data at preoperative, three months, six months, one year, and two years postoperative were collected. Statistical analysis was performed using Student’s T-tests, χ2binomial correlation, odds ratios, logistic regression, and Mean Clinically Important Difference (MCID).

RESULTS: A total of 156 patients were included (60 male, 96 female) with mean age 62.6±11.1 years at surgery. Thirty-nine (25%) had depression and/or anxiety (DA). Baseline Oswestry Disability Index (ODI) and EQ5D scores were significantly worse in the DA cohort compared to controls (ODI 51.1±18.3 vs. 42.9±15.8; p=0.010, EQ5D 0.46±0.21 vs. 0.57±0.21; p=0.005). Both cohorts experienced similar relative improvement at two years (delta ODI -18.2±27.9 vs. -17.8±22.1; p=0.924, EQ5D 6.8±33.8 vs 8.1±32.9; p=0.830). Absolute outcome scores were worse in the DA cohort at all intervals. DA were not independently predictive of changes in PROMs (delta ODI mean difference 4.49, r2=0.36, p=0.924).

: The present study showed similar improvement in PROMs following lumbar fusion for patients with anxiety and depression compared to healthy controls. These data suggest these patients are no less likely to benefit from appropriately planned lumbar fusion.

PMID:38575064 | DOI:10.1016/j.wneu.2024.03.148

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Impact of depression and anxiety on patient reported outcomes measures after lumbar fusion

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World Neurosurg. 2024 Apr 2:S1878-8750(24)00534-5. doi: 10.1016/j.wneu.2024.03.148. Online ahead of print. ABSTRACT INTRODUCTION: Depression and anxiety are common in patients undergoing spinal surgery and might negatively impact outcomes. This study investigates the possible effect of these diagnoses on patient reported outcomes following lumbar fusion. METHODS: Retrospective review of a registry containing prospectively collected data of

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