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Imaging Features of Early Diffuse Idiopathic Skeletal Hyperostosis (pre-DISH): Analysis of Progression of Ligament Ossification over 5 Years by Computed Tomography – Lumbar Fusion

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This article published in Spine Surgery and Related Research aims to define the preclinical stage of diffuse idiopathic skeletal hyperostosis (DISH) by analyzing the change in ossification extent in each intervertebral space in the thoracic and lumbar spines over time using computed tomography (CT). The study enrolled 188 patients who underwent CT scans at an interval of 5 years to 5 years and 2 months. The prevalence of DISH and pre-DISH was investigated, and it was found that patients with three contiguous intervertebral spaces showing a modified Mata score of 2 or 3 points should be considered pre-DISH. The study provides useful insights into identifying pre-DISH, which can help in the early diagnosis and management of DISH

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative day surgery spinal centre in UK

Published article

S: Patients who have three contiguous intervertebral spaces with a modified Mata score of 2 or 3 points should be considered pre-DISH.

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Spine Surg Relat Res. 2023 Apr 21;7(5):443-449. doi: 10.22603/ssrr.2022-0226. eCollection 2023 Sep 27.ABSTRACTINTRODUCTION: Some patients who have not been diagnosed with diffuse idiopathic skeletal hyperostosis (DISH) (patients in the preclinical stage of DISH [pre-DISH]) may develop DISH in the future. However, there are currently no clearly defined diagnostic criteria for pre-DISH. This study aims to,

Spine Surg Relat Res. 2023 Apr 21;7(5):443-449. doi: 10.22603/ssrr.2022-0226. eCollection 2023 Sep 27.

ABSTRACT

INTRODUCTION: Some patients who have not been diagnosed with diffuse idiopathic skeletal hyperostosis (DISH) (patients in the preclinical stage of DISH [pre-DISH]) may develop DISH in the future. However, there are currently no clearly defined diagnostic criteria for pre-DISH. This study aims to define pre-DISH by analyzing the change in the ossification extent in each intervertebral space in the thoracic and lumbar spines over time using computed tomography (CT).

METHODS: Of the patients who underwent CT of the thoracic to pelvic region at least twice from 2009 to 2018, 188 who underwent CT at an interval of 5 years to 5 years and 2 months were enrolled. The prevalence of DISH during the first and second CT scans was investigated. The pre-DISH feature was defined, and the prevalence of pre-DISH on the first CT and the change after 5 years in patients with pre-DISH was investigated.

RESULTS: Of the 188 patients, 37 (19.7%) and 48 (25.5%) were diagnosed with DISH on the first and second CT scans, respectively. Pre-DISH was defined as the ossification characterized by the modified Mata score of three contiguous intervertebral spaces with a score of ≥2 points (222; 2 points, ligament ossification of half or more of the intervertebral disc height but incomplete fusion), and 52 patients were diagnosed with pre-DISH. Of the 52 patients with a score of ≥(222), 11 (21.2%) were diagnosed with DISH 5 years later.

S: Patients who have three contiguous intervertebral spaces with a modified Mata score of 2 or 3 points should be considered pre-DISH.

PMID:37841032 | PMC:PMC10569810 | DOI:10.22603/ssrr.2022-0226

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Imaging Features of Early Diffuse Idiopathic Skeletal Hyperostosis (pre-DISH): Analysis of Progression of Ligament Ossification over 5 Years by Computed Tomography

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Spine Surg Relat Res. 2023 Apr 21;7(5):443-449. doi: 10.22603/ssrr.2022-0226. eCollection 2023 Sep 27.ABSTRACTINTRODUCTION: Some patients who have not been diagnosed with diffuse idiopathic skeletal hyperostosis (DISH) (patients in the preclinical stage of DISH [pre-DISH]) may develop DISH in the future. However, there are currently no clearly defined diagnostic criteria for pre-DISH. This study aims to

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