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Fusion Assessment of Oblique Lumbar Interbody Fusion Using Demineralized Bone Matrix: A 2-Year Prospective Study – Lumbar Fusion

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The article explores the effectiveness of oblique lumbar interbody fusion (OLIF) surgery using allografts and dimerized bone matrix (DBM) rather than autografts. The study involved 79 patients who underwent OLIF followed by percutaneous pedicle screw fixation. Radiographic and clinical follow-ups were conducted at 12, 18, and 24 months post-surgery. The results showed significant improvements in back pain, leg pain, and disability index scores. Subsidence was observed in 35.4% of cases at 12 months, increasing to 47.9% and 50.0% at 1.5 years and 2 years, respectively. The solid fusion rate after OLIF increased from 32.3% at 1 year to 72.9% at 2 years. The study concludes that OLIF using allografts and DBM is a safe and effective procedure for treating degenerative lumbar diseases, achieving satisfactory fusion rates within 2 years

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most experienced spine centre in London

Published article

: OLIF is a safe and effective surgical procedure for the treatment of degenerative lumbar diseases. The mBSF scale, which simultaneously evaluates both dynamic angles and bone bridge formation, offers great reliability for the radiological assessment of fusion. Moreover, OLIF using allografts and DBM, which is performed on one or 2 levels at L2-5, can achieve satisfactory fusion rates within 2 years after surgery.

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Neurospine. 2023 Dec;20(4):1205-1216. doi: 10.14245/ns.2347032.516. Epub 2023 Dec 31.ABSTRACTOBJECTIVE: Although several studies have reported successful fusion rates after oblique lumbar interbody fusion (OLIF) using allografts or dimerized bone matrix (DBM) instead of autografts, whether OLIF can achieve satisfactory solid fusion without the use of autografts remains unclear. This study investigated the real fusion rates after,

Neurospine. 2023 Dec;20(4):1205-1216. doi: 10.14245/ns.2347032.516. Epub 2023 Dec 31.

ABSTRACT

OBJECTIVE: Although several studies have reported successful fusion rates after oblique lumbar interbody fusion (OLIF) using allografts or dimerized bone matrix (DBM) instead of autografts, whether OLIF can achieve satisfactory solid fusion without the use of autografts remains unclear. This study investigated the real fusion rates after OLIF using allografts and DBM, which were evaluated using both dynamic radiographs and computed tomography scans.

METHODS: We enrolled 79 consecutive patients who underwent minimally invasive OLIF followed by percutaneous pedicle screw fixation. All patients were treated with OLIF between L2 and L5 and underwent radiographic and clinical follow-ups at 12, 18, and 24 months after surgery. Radiographic assessment of fusion was performed using the modified BrantigaSteffee-Fraser (mBSF) scale, which was categorized as follows: grades I (radiographic pseudoarthrosis), II (indeterminate fusion), and III (solid radiographic fusion). Other radiologic and clinical outcomes were evaluated using the following parameters: vertebral slippage distance, disc height, subsidence, Oswestry Disability Index (ODI), and visual analogue scale (VAS).

RESULTS: Clinical outcomes demonstrated significant improvements in the VAS scores for back pain, leg pain, and ODI after surgery. Subsidence was present in 34 cases (35.4%) at 12 months postoperatively, which increased to 47.9% and reached 50.0% at 1.5 years and 2 years after surgery, respectively. The solid fusion rate after OLIF was 32.3% at 1 year, increased to 58.3% at 1.5 years, and reached 72.9% at 2 years. Radiographic pseudoarthrosis was 24.0% at 1 year, which decreased to 6.3% at 1.5 years and 3.1% at 2 years.

: OLIF is a safe and effective surgical procedure for the treatment of degenerative lumbar diseases. The mBSF scale, which simultaneously evaluates both dynamic angles and bone bridge formation, offers great reliability for the radiological assessment of fusion. Moreover, OLIF using allografts and DBM, which is performed on one or 2 levels at L2-5, can achieve satisfactory fusion rates within 2 years after surgery.

PMID:38171289 | DOI:10.14245/ns.2347032.516

The London Spine Unit : most experienced spine centre in London

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Fusion Assessment of Oblique Lumbar Interbody Fusion Using Demineralized Bone Matrix: A 2-Year Prospective Study

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Neurospine. 2023 Dec;20(4):1205-1216. doi: 10.14245/ns.2347032.516. Epub 2023 Dec 31.ABSTRACTOBJECTIVE: Although several studies have reported successful fusion rates after oblique lumbar interbody fusion (OLIF) using allografts or dimerized bone matrix (DBM) instead of autografts, whether OLIF can achieve satisfactory solid fusion without the use of autografts remains unclear. This study investigated the real fusion rates after

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