Extragonadal germ cell tumor of the posterior mediastinum in a toddler difficult with spinal twine compression: a case report.
BMC Pediatr. 2018 Mar 05;18(1):97
Authors: Yon DK, Ahn TK, Shin DE, Kim GI, Kim MK
BACKGROUND: Germ cell tumors (GCTs) in youngsters are uncommon neoplasms with numerous pathological findings in response to the positioning and age of presentation. The most typical signs in youngsters with mediastinal GCTs, that are nonspecific, are dyspnea, chest ache, cough, hemoptysis, vena cava occlusion syndrome, and fatigue/weak spot. Due to these nonspecific signs, it’s troublesome to suspect a mediastinal mass. A posterior mediastinal tumor inflicting spinal twine compression is a crucial instance of an oncologic emergency arising from a neurogenic tumor.
CASE PRESENTATION: Youngsters with posterior mediastinum GCTs will be simply mistaken as having a neurogenic tumor due to web site of tumor origin. We handled our 7-year-old affected person with emergency decompression surgical procedure and high-dose steroid pulse remedy to stop secondary damage to the spinal twine. Major damage was a results of spinal twine compression as a result of preliminary manifestation of GCT within the posterior mediastinum. Cisplatin-based chemotherapy was additionally administered. The affected person was adopted up frequently for three years and is present process rehabilitation with none indicators of recurrence.
CONCLUSIONS: We current a particularly uncommon case of a kid with paraparesis brought on by extradural spinal twine compression because the preliminary manifestation of GCT within the posterior mediastinum. The kid was handled with emergency decompression surgical procedure and high-dose pulse steroid remedy to stop secondary damage to the spinal twine.
PMID: 29506496 [PubMed – in process]