Govt perform impairments in fibromyalgia syndrome: Relevance of medical variables and physique mass index.
PLoS One. 2018;13(four):e0196329
Authors: Muñoz Ladrón de Guevara C, Fernández-Serrano MJ, Reyes Del Paso GA, Duschek S
BACKGROUND: A number of investigations recommend the presence of decay of govt perform in fibromyalgia syndrome (FMS). The research quantified govt capabilities in sufferers with FMS. A big selection of capabilities was assessed, together with updating, shifting and inhibition, in addition to resolution making and psychological planning. Furthermore, medical variables have been investigated as potential mediators of govt dysfunction, together with ache severity, psychiatric comorbidity, medicine and physique mass index (BMI).
METHODS: Fifty-two FMS sufferers and 32 wholesome controls accomplished a battery of 14 neuropsychological assessments. Medical interviews have been carried out and the McGill Ache Questionnaire, Beck Melancholy Stock, State-Trait Anxiousness Stock, Fatigue Severity Scale and Oviedo High quality of Sleep Questionnaire have been introduced.
RESULTS: Sufferers carried out poorer than controls on the Letter Quantity Sequencing, Arithmetic and Similarities subtests of the Wechsler Grownup Intelligence Scale, the Spatial Span subtest of the Wechsler Reminiscence Scale, an N-back job, a verbal fluency job, the Ruff Figural Fluency Check, the Inhibition rating of the Stroop Check, the Inhibition and Shifting scores of the 5 Digits Check, the Key Search Check and the Zoo Map Job. Furthermore, sufferers exhibited much less steep studying curves on the Iowa Playing Job. Amongst medical variables, BMI and ache severity defined the most important proportion of efficiency variance.
CONCLUSIONS: This research demonstrated impairments in govt capabilities of updating, shifting inhibition, resolution making and planning in FMS. Whereas the mediating function of ache in cognitive impairments in FMS had been beforehand established, the affect of BMI is a novel discovering. Obese and weight problems needs to be thought-about by FMS researchers, and within the therapy of the situation.
PMID: 29694417 [PubMed – in process]