Ewing Sarcoma of the Cervical Epidural Area Presenting with Tetraplegia: Case Report and Assessment of Literature.
World Neurosurg. 2017 Nov;107:1046.e9-1046.e15
Authors: Kutty RK, Peethambaran A, Sunilkumar BS, Balachandran Nair KG, Korde P, Jain SK
BACKGROUND: Ewing sarcoma (ES) is among the many most frequented extremity osseous tumor in childhood. It was first described by James Ewing as diffuse endotheliomas in 1921. The title Ewing sarcoma was coined by Oberling in 1928 as a tribute to the legend who described this illness. ES exists in osseous and extraosseous types. It shares a lot of its molecular typing with primitive neuroectodermal tumor (PNET); therefore, they’re thought to be totally different ends of the identical molecular spectrum. ES, extraosseous ES, PNET, and Askins tumor are the opposite members of this household termed the Ewing sarcoma household of tumors. Extraosseous ES has been described in varied areas of the backbone, however its incidence within the cervical epidural area is rare.
CASE DESCRIPTION: A 12-year-old youngster introduced to us with neck ache and progressive weak spot of all four limbs. She was investigated and located to have a extremely vascular lesion within the cervical epidural area extending from C2 to the C4 area. Embolization remedy was unsuccessful. She deteriorated and ultimately needed to bear emergency surgical procedure to decompress the spinal twine. The lesion was biopsied and recognized as extraosseous ES. After radiotherapy and chemotherapy, the affected person regained many of the energy in her limbs.
CONCLUSION: Extraosseous ES is a uncommon tumor of the cervical twine on this age group. We report this case to spotlight the difficulties encountered within the administration of this variant.
PMID: 28797979 [PubMed – indexed for MEDLINE]