Endovascular Remedy of Spinal Vascular Lesion in Japan: Japanese Registry of Neuroendovascular Remedy (JR-NET) and JR-NET2.
Neurol Med Chir (Tokyo). 2014;54 Suppl 2:72-Eight
Authors: Tsuruta W, Matsumaru Y, Miyachi S, Sakai N
A subgroup evaluation of spinal vascular lesions within the Japanese Registry of Neuroendovascular Remedy (JR-NET) and JR-NET2, retrospective registry research carried out in 2005–2009, was carried out to grasp the present standing of therapy in Japan. Of 201 spinal lesions enrolled, 98 analyzable instances of spinal dural arteriovenous fistula (SDAVF), 43 of spinal perimedullary arteriovenous fistula (SPAVF), and 23 of spinal intramedullary arteriovenous malformation (SIAVM) had been assessed. Remedy was radical within the majority (83.6%) of SDAVF, palliative within the majority (70.6%) of SIAVM, and radical and palliative in an identical variety of instances of SPAVF. Complete occlusion was achieved in 26 (54.2%) SDAVF instances, 9 (29.zero%) SPAVF, and four (23.5%) SIAVM. Remedy-related problems occurred in three (three.1%) SDAVF instances, 7 (16.three%) SPAVF, and 1 (four.three%) SIAVM. Put up-treatment neurological enchancment was achieved in 49 (50.zero%) of SDAVF instances, 15 (34.9%) SPAVF, and 5 (21.7%) SIAVM. The modified Rankin Scale (mRS) of zero, 1, or 2 on postoperative day 30, the first endpoint, was achieved in 62 (63.three%) SDAVF instances, 26 (60.5%) SPAVF, and 12 (52.2%) SIAVM. The mRS of zero–2 on postoperative day 30 was correlated with presymptomatic mRS of zero–2 [P<0.0001, odds ratio (OR): 42.88, 95% confidence interval (CI): 14.83–123.97] and postoperative neurological enchancment (P=zero.046, OR: 2.57, 95% CI: 1.02–6.48). In Japan, endovascular therapy of spinal vascular lesions was administered safely. Good mRS on postoperative day 30 was extremely correlated with good pre-symptomatic mRS, suggesting necessity of early prognosis and therapy.
PMID: 26236818 [PubMed – indexed for MEDLINE]