Effectiveness of fixed-site high-frequency transcutaneous electrical nerve stimulation in persistent ache: a large-scale, observational research.
J Ache Res. 2018;11:703-714
Authors: Kong X, Gozani SN
Goal: The target of this research was to evaluate the effectiveness of fixed-site high-frequency transcutaneous electrical nerve stimulation (FS-TENS) in a real-world persistent ache pattern.
Background: There’s a want for nonpharmacological remedy choices for persistent ache. FS-TENS improved multisite persistent ache in a earlier interventional research. Giant observational research are wanted to additional characterize its effectiveness.
Strategies: This retrospective observational cohort research examined adjustments in persistent ache measures following 60 days of FS-TENS use. The research knowledge had been obtained from FS-TENS customers who uploaded their machine utilization and scientific knowledge to an internet database. The first consequence measures had been adjustments in ache depth and ache interference with sleep, exercise, and temper on an 11-point numerical score scale. Dose-response associations had been evaluated by stratifying topics into low (?30 days), intermediate (31-56 days), and excessive (?57 days) utilization subgroups. FS-TENS effectiveness was quantified by baseline to follow-up group variations and a responder evaluation (?30% enchancment in ache depth or ?2-point enchancment in ache interference domains).
Outcomes: Utilization and scientific knowledge had been collected from 11,900 folks utilizing FS-TENS for persistent ache, with 713 machine customers assembly the inclusion and exclusion standards. Examine topics had been typically older, obese adults. Topics reported multisite ache with a imply of four.eight (customary deviation [SD] 2.5) ache websites. A complete of 97.2% of topics recognized low again and/or decrease extremity ache, and 72.9% of topics reported higher physique ache. All ache measures exhibited statistically vital group variations from baseline to 60-day follow-up. The most important adjustments had been ache interference with exercise (-Zero.99±2.69 factors) and temper (-1.02±2.78 factors). A complete of 48.7% of topics exhibited a clinically significant discount in ache interference with exercise or temper. This proportion elevated to 57.1% for the excessive utilization subgroup.
Conclusion: FS-TENS is a sensible possibility for treating multisite persistent ache. The best influence is on ache interference with exercise and temper. FS-TENS utilization and effectiveness exhibit a dose-response affiliation, suggesting that every day use maximizes ache reduction.
PMID: 29670397 [PubMed]