Impact of pure muscle retraction on multifidus damage and atrophy after posterior lumbar backbone surgical procedure with 24 weeks commentary in a rabbit mannequin.
Eur Backbone J. 2017 Jan;26(1):210-220
Authors: Hu ZJ, Zhang JF, Xu WB, Zhao FD, Wang JY, Fan SW, Fang XQ
PURPOSE: To judge the impact of pure muscle retraction on multifidus damage and atrophy.
MATERIALS AND METHODS: Sixty-three grownup New Zealand white rabbits had been divided evenly into three teams: 1-h retraction (group R1), 2-h retraction (R2), and sham surgical procedure (C). The multifidus muscle was evaluated utilizing magnetic resonance imaging (MRI) and histology after three and 48 h, and 1, three, 6, 12, and 24 weeks after surgical procedure.
RESULTS: Multifidus muscle damage and atrophy weren’t noticed in group C, however had been apparent in teams R1 and R2. Edema, necrosis, and irritation primarily occurred within the first week postoperatively, and had been extra extreme in R2 than in R1 (P < zero.01). Muscle fiber regeneration started at week 1, fibrotic adjustments primarily occurred at weeks three and 6, and fats degeneration grew to become apparent at weeks 12 and 24 postoperatively. The fibrosis and fats degeneration scores of R2 had been greater than these of R1 (P < zero.01). Decreased acetylcholine exercise and granular degeneration of the neuromuscular junction had been noticed in each retraction teams, however was extra extreme in R2 than in R1 (P < zero.01).
CONCLUSION: Muscle retraction was an vital issue not just for multifidus damage, but in addition for long-term multifidus atrophy after posterior lumbar surgical procedure; an extended retraction time brought on extra extreme multifidus damage and atrophy. Muscle fibers will be regenerated postoperatively, and denervation is likely to be the explanation for muscle atrophy.
PMID: 26687124 [PubMed – indexed for MEDLINE]