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Effect of Preoperative Marijuana on Patient Outcomes and Opioid Use after Lumbar Decompression – Lumbar Fusion

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This article is a retrospective cohort study that examines the impact of preoperative marijuana use on outcomes and postoperative opioid use in patients who underwent lumbar decompression without fusion. The study analyzed patient data from 2017-2022 and performed a propensity match to compare marijuana users and non-users. The results showed that preoperative marijuana use did not significantly affect medical complications, readmissions, or opioid consumption. However, there was a trend suggesting that marijuana users had a higher likelihood of reoperations. The study concludes that while marijuana use does not impact certain outcomes, it is a significant predictor of future postoperative reoperations. Further research is needed to understand the role of marijuana use in spine surgery

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : finest day surgery spinal centre in London

Published article

S: In lumbar decompression patients, preoperative marijuana use does not impact opioid consumption, readmissions, or medical complications, but is a significant predictor of future postoperative reoperations. Additional research is necessary to further explore the role of marijuana use in spine surgery.

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Global Spine J. 2023 Sep 20:21925682231203650. doi: 10.1177/21925682231203650. Online ahead of print.ABSTRACTSTUDY DESIGN: Retrospective Cohort Study.OBJECTIVES: Our study aims to analyze the effect of preoperative marijuana use on outcomes and postoperative opioid use in patients who have undergone lumbar decompression without fusion.METHODS: All patients >18 years of age who underwent lumbar decompression from 2017-2022 with,

Global Spine J. 2023 Sep 20:21925682231203650. doi: 10.1177/21925682231203650. Online ahead of print.

ABSTRACT

STUDY DESIGN: Retrospective Cohort Study.

OBJECTIVES: Our study aims to analyze the effect of preoperative marijuana use on outcomes and postoperative opioid use in patients who have undergone lumbar decompression without fusion.

METHODS: All patients >18 years of age who underwent lumbar decompression from 2017-2022 with documented preoperative marijuana use at our academic institution were retrospectively identified. A 3:1 propensity match incorporating demographics, procedure type, and levels decompressed was performed to compare preoperative marijuana users and non-users. 1-year preoperative and postoperative opioid consumption in milligrams of morphine equivalents and postoperative outcomes including readmissions, reoperations, and complications, were obtained. A multivariate regression model was performed to measure the effect of marijuana use on the likelihood of a spine reoperation.

RESULTS: Of the 340 included patients, 85 were preoperative marijuana users. There were no significant differences in medical complications, 90-day readmissions, or opioid consumption preoperatively or postoperatively (P > .05). We identified a trend towards patients who used marijuana having more reoperations for any cause (20.0% vs 11.37%, P = .067). Multivariate logistic regression analysis suggested that preoperative marijuana use was a significant predictor of all-spine reoperations (OR = 2.06, P = .036).

S: In lumbar decompression patients, preoperative marijuana use does not impact opioid consumption, readmissions, or medical complications, but is a significant predictor of future postoperative reoperations. Additional research is necessary to further explore the role of marijuana use in spine surgery.

PMID:37728558 | DOI:10.1177/21925682231203650

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Read the original publication:

Effect of Preoperative Marijuana on Patient Outcomes and Opioid Use after Lumbar Decompression

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Global Spine J. 2023 Sep 20:21925682231203650. doi: 10.1177/21925682231203650. Online ahead of print.ABSTRACTSTUDY DESIGN: Retrospective Cohort Study.OBJECTIVES: Our study aims to analyze the effect of preoperative marijuana use on outcomes and postoperative opioid use in patients who have undergone lumbar decompression without fusion.METHODS: All patients >18 years of age who underwent lumbar decompression from 2017-2022 with

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