Cervical Disc ArthroplastyThe London Spine Unit : finest spinal hospital in UKPublished articleBACKGROUND: Quantitative bone re-modelling theories suggest that bones adapt to mechanical loading conditions. Follow-up studies have shown that total disc replacement (TDR) modifies stress patterns in the bones, leading to heterotopic ossification (HO). Although there are a few studies on HO using finite element models (FEM), its effect on the adjacent levels and change in range of motion (ROM) have not been adequately investigated. This study interfaces the HO using bone re-modelling algorithm…Cervical Disc Arthroplasty Expert. Best Spinal Surgeon UKThe London Spine Unit is a specialist clinic for Cervical Disc Arthoplasty as Day Surgery.
Methods: A FEM of the human cervical spine (C3-C7) was developed for this study, with material properties obtained from literature. The motion of the segments in the sagittal, frontal and transverse planes under combined loading conditions of 1 Nm moment and 73.6 N compression were validated against experimental corridors. The natural disc between the C5-C6 segment was replaced with the Bryan artificial cervical disc, and changes in sagittal ROM were compared before and after HO. The process of HO was simulated using a bone remodelling algorithm using strain energy density (SED) as the mechanical stimuli.
Results and Our study demonstrates the feasibility of using SED calculations from the flexion-extension loading conditions for prediction of HO after ADR. The current findings suggest that the nature of trabecular stresses, and the subsequent rate and location of HO formation could differ based on the geometric design and nature of constraint for different artificial discs. The Bryan disc significantly reduced ROM at the implanted level in flexion. However, in extension, ROM increased at the implanted level and decreased slightly at the adjacent levels. After HO, ROM drastically reduced at the implanted level in both extension and flexion, and showed a minor increase in the adjacent levels, indicating that biomechanical behavior of high-grade HO is similar to a fused segment, thereby reducing the intended and initial motion preservation.
Keywords: Cervical arthroplasty; Cervical spine; Finite element method; Heterotopic ossification; Range of motion.
The London Spine Unit : finest spinal hospital in UKRead the original publication from Pubmed : Effect of heterotopic ossification after bryan-cervical disc arthroplasty on adjacent level range of motion: A finite element study