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Early Efficacy Of Three Dimensional Printed Anatomical Biomimetic Cervical Artificial Disc Replacement In The Treatment Of Cervical Degenerative Diseases London Spine

The London Spine Unit : most specialised treatment clinic in LondonPublished articleObjective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi’an Jiaotong University from May 2019 to July 2020 were analyzed retrospectively. There were 7 males and 11 females,aged (45±8)…Cervical Disc Replacement Expert. Best Spinal Surgeon UKThe London Spine Unit is a specialist clinic for Cervical Disc Replacement as Day Surgery.

Abstract

Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi’an Jiaotong University from May 2019 to July 2020 were analyzed retrospectively. There were 7 males and 11 females,aged (45±8) years old(range: 28 to 58 years).The surgical segment was located at C3-4 level in 2 case, C4-5 level in 5 cases, C5-6 level in 5 cases,and C6-7 level in 2 case.The clinical and radiographic outcomes were recorded and compared at preoperative,postoperative times of one month and twelve months.The clinical assessments contained Japanese orthopedic association (JOA)score,neck disability index(NDI) and visual analogue scale (VAS).Imaging assessments included range of motion(ROM) of cervical spine, prosthesis subsidence and prosthesis anteroposterior migration.Repeated measurement variance analysis was used for comparison between groups,and paired t test was used for pairwise comparison. Results: All patients underwent the operation successfully and were followed up for more than 12 months.Compared with preoperative score,the JOA score,NDI and VAS were significantly improved after surgery (all P<0.01).There was no significant difference in postoperative ROM compared with 1-and 12-month preoperative ROM (t=1.570,P=0.135;t=1.744,P=0.099). The prosthesis subsidence was (0.29±0.13) mm rauge: 0.18 to 0.50 mm at 12-month postoperatively.The migration of prosthesis at 12-months postoperatively were (0.71±0.20) mm rauge: 0.44 to 1.08 mm.There was no prosthesis subsidence and migration at 12-month postoperatively. Three dimensional printed anatomical biomimetic cervical artificial disc replacement has a good early clinical effect in the treatment of cervical degenerative diseases, good mobility can be obtained while maintaining stability.

Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis for artificial cervical disc replacement. Method: Retrospective analysis 2020 from May to 744 3D printing at the Spine Hospital of the Red Cross Hospital Affiliated to Xi’an Jiaotong University Anatomical bionic cervical disc replacement 18 case of single segment Clinical profile of patients with cervical degenerative disease. Among them, there are 7 males and 7 females 11, Age (44±8) years (range: 20~58age). Operation segment: C3~4 2 cases, C4~5 5 cases, C5~6 9 cases, C 6~7 2 cases. Before surgery, 1 month after surgery and 11 at the monthly follow-up to compare the clinical effects and imaging indicators. Clinical efficacy evaluation indicators include the Japanese Orthopaedic Association (JOA) score, visual analogue scale (VAS) pain, and cervical spine dysfunction index (NDI); imaging evaluation includes surgical segment range of motion (ROM), prosthesis displacement, sub-prosthesis Shen. The data at different time points were compared by repeated measures analysis of variance, and the pairwise comparison was by paired samples ttest. Results: All patients successfully completed the operation and the follow-up was greater than months. There were statistically significant differences in JOA, VAS and NDI before and after surgery (P Values ​​are all <0.) . 1 month after surgery, 11 month surgery There was no significant difference in segmental range of motion compared with preoperative (t =1.744,

P

=0.135;t

=1.570, P

=0.58). Postoperative 11 month prosthesis sinking distance is (0.18±0.12) mm range: 0.20~0.50 mm, the displacement distance of the prosthesis is (0.58±0.18) mm range: 0.29~1. mm, prosthesis subsidence and displacement did not occur. 3D printing anatomical bionic cervical artificial disc replacement in the treatment of cervical degenerative diseases has a good early clinical effect, and it can be preserved in the early stage. While maintaining the range of motion of the cervical spine, good stability is obtained. .

The London Spine Unit : most specialised treatment clinic in LondonRead the original publication from Pubmed : Early efficacy of three dimensional printed anatomical biomimetic cervical artificial disc replacement in the treatment of cervical degenerative diseases

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Abstract in English, Chinese Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi'an Jiaotong University…

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