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Early Efficacy Of Three Dimensional Printed Anatomical Biomimetic Cervical Artificial Disc Replacement In The Treatment Of Cervical Degenerative Diseases – Cervical Disc Replacement

The article discusses the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. The study analyzed the clinical data of 18 patients who underwent the procedure and followed up for more than 12 months. The results showed that the clinical assessments, including the Japanese orthopedic association (JOA) score, neck disability index (NDI), and visual analogue scale (VAS), were significantly improved after surgery. The range of motion (ROM) of the cervical spine was not significantly different compared to preoperative measurements. The study also found minimal prosthesis subsidence and migration at 12-month postoperatively. Overall, the three-dimensional printed anatomical biomimetic cervical artificial disc replacement showed good early clinical effects in the treatment of cervical degenerative diseases while maintaining stability and mobility

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
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Published article

Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi’an Jiaotong University from May 2019 to July 2020 were analyzed retrospectively. There were 7 males and 11 females,aged (45±8)…

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Abstract in English, Chinese Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi’an Jiaotong University,

Abstract

Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi’an Jiaotong University from May 2019 to July 2020 were analyzed retrospectively. There were 7 males and 11 females,aged (45±8) years old(range:28 to 58 years).The surgical segment was located at C3-4 level in 2 cases, C4-5 level in 5 cases, C5-6 level in 9 cases, and C6-7 level in 2 cases.The clinical and radiographic outcomes were recorded and compared at preoperative,postoperative times of one month and twelve months.The clinical assessments contained Japanese orthopedic association (JOA) score,neck disability index (NDI) and visual analogue scale (VAS).Imaging assessments included range of motion (ROM) of cervical spine, prosthesis subsidence and prosthesis anteroposterior migration.Repeated measurement variance analysis was used for comparison between groups,and paired t test was used for pairwise comparison. Results: All patients underwent the operation successfully and were followed up for more than 12 months.Compared with preoperative score,the JOA score,NDI and VAS were significantly improved after surgery (all P<0.01).There was no significant difference in postoperative ROM compared with 1-and 12-month preoperative ROM (t=1.570,P=0.135;t=1.744,P=0.099). The prosthesis subsidence was (0.29±0.13) mm (range: 0.18 to 0.50 mm) at 12-month postoperatively.The migration of prosthesis at 12-months postoperatively were (0.71±0.20) mm (range: 0.44 to 1.08 mm).There was no prosthesis subsidence or migration>2 mm at 12-month postoperatively. Three dimensional printed anatomical biomimetic cervical artificial disc replacement has a good early clinical effect in the treatment of cervical degenerative diseases, good mobility can be obtained while maintaining stability.

Purpose: To investigate the effectiveness and safety of a new type of cervical artificial disc prosthesis in artificial cervical disc replacement. method: From May 2019 to July 2020, the clinical data of 18 patients with single-segment cervical degenerative disease treated with three-dimensional printed anatomical bionic cervical disc replacement in the Spine Hospital of Honghui Hospital Affiliated to Xi’an Jiaotong University were retrospectively analyzed. Among them, there were 7 males and 11 females, aged (45±8) years old (range: 28~58 years old). Surgical segment: C3~4 2 cases, C4~5 5 cases, C5~6 9 cases, C6~7 2 cases. The clinical effects and imaging indicators were compared before operation, 1 month after operation and 12 months follow-up. Clinical efficacy evaluation indicators include Japanese Orthopedic Association (JOA) score, pain visual analogue scale (VAS), cervical dysfunction index (NDI); imaging evaluation indicators include surgical segment range of motion (ROM), prosthesis displacement, prosthesis sink.Repeated measures analysis of variance was used to compare data at different time points, and paired samples were used for pairwise comparisonsttest. result: All patients successfully completed the operation and were followed up for more than 12 months. There were statistically significant differences in JOA score, VAS, and NDI before and after surgery (Pvalues ​​are all <0.01). There was no statistically significant difference in the range of motion of the surgical segment at 1 month and 12 months after operation compared with that before operation (t=1.570,P=0.135;t=1.744,P=0.099). At 12 months after operation, the subsidence distance of the prosthesis was (0.29±0.13) mm (range: 0.18-0.50 mm), and the displacement distance of the prosthesis was (0.71±0.20) mm (range: 0.44-1.08 mm), without prosthesis Subsidence or displacement > 2 mm cases. in Three-dimensional printed anatomical bionic cervical artificial disc replacement has good early clinical effect in the treatment of cervical degenerative diseases, and can obtain good stability while retaining the range of motion of the cervical spine. .

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Early efficacy of three dimensional printed anatomical biomimetic cervical artificial disc replacement in the treatment of cervical degenerative diseases

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Abstract in English, Chinese Objective: To investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases. Methods: The clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi'an Jiaotong University
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