Does T1- and diffusion-weighted magnetic resonance imaging give value-added than bone scintigraphy within the follow-up of vertebral metastasis of prostate most cancers?
Investig Clin Urol. 2017 Sep;58(5):324-330
Authors: Lee DH, Nam JK, Jung HS, Kim SJ, Chung MK, Park SW
PURPOSE: To guage the effectiveness of restricted Magnetic Resonance (MR) pictures together with T1- and diffusion-weighted picture (DWI) for monitoring vertebral metastasis in sufferers with prostate most cancers.
MATERIALS AND METHODS: From July 2014 to November 2016, sufferers identified with spinal metastasis from prostate most cancers utilizing 99mTc bone scintigraphy have been enrolled. Whatever the main native remedy, the modifications in spinal metastasis have been adopted up utilizing bone scan and biparametric MR (T1+DWI). All assessments have been adopted up for greater than three months.
RESULTS: Among the many 14 follow-ups of 10 sufferers, 6 and 10 (together with all progressed instances on bone scan) follow-ups have been decided to point out progressive illness utilizing bone scan and biparametric MR, respectively. In any other case, we may have predicted neurologic sequela earlier utilizing biparametric MR. Examination time for biparametric MR was 15 minutes, and it was four hours for bone scan, respectively.
CONCLUSIONS: Though bone scan has been thought-about the usual check for bony metastasis in males with prostate most cancers, restricted MR together with T1 and DWI has an extra profit in monitoring spinal metastasis in sufferers who’re already identified as having spinal metastasis. The restricted MR is extra delicate in detecting progressive illness. As well as, it will possibly cut back neurologic issues brought on by spinal metastasis.
PMID: 28868503 [PubMed – indexed for MEDLINE]