19 Harley St, London, W1G 9QJ, UK

Diabetes Mellitus And Poor Glycemic Control Are Associated With A Higher Risk Of Lumbar Spinal Stenosis: An Analysis Of A Large Nationwide Database London Spine Lumbar Stenosis

The article discusses a large-scale retrospective case-control study that examined the relationship between diabetes and the development of lumbar spinal stenosis. The study found that diabetic patients had a higher likelihood of being diagnosed with lumbar spinal stenosis compared to non-diabetic individuals. Factors such as poor glycemic control, diabetes duration, and diabetes-related complications further increased this risk. Prolonged diabetes exposure also increased the risk of developing lumbar spinal stenosis. Additionally, the study found that diabetes diagnosis reduced median survival by around 4.5 years for both stenosis and non-stenosis patients. The article concludes that recognizing the adverse relationship between diabetes and lumbar spinal stenosis is important in clinical practice and public health measures

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : best situated treatment clinic in London

Published article

Diabetic patients with prolonged disease, poor glycemic control, and diabetes-related complications face an elevated risk of developing lumbar spinal stenosis. Recognizing the reciprocal adverse relationship between these conditions is crucial in clinical practice and designing public health measures for managing both conditions.

Spine Lumbar Spinal Stenosis Expert. Best Spinal Surgeon UK
Abstract Study design: A large-scale retrospective case-control study. Objective: Examine diabetes as a risk factor for lumbar spinal stenosis development and evaluate the impact of diabetes duration, glycemic control, and associated complications on this risk. Summary of background data: Diabetes mellitus, a multiorgan disorder impacting various connective tissues, induces histological changes in spinal structures, particularly,

Abstract

Study design: A large-scale retrospective case-control study.

Objective: Examine diabetes as a risk factor for lumbar spinal stenosis development and evaluate the impact of diabetes duration, glycemic control, and associated complications on this risk.

Summary of background data: Diabetes mellitus, a multiorgan disorder impacting various connective tissues, induces histological changes in spinal structures, particularly the ligamentum flavum. While clinical studies suggest a higher incidence of lumbar spinal stenosis in diabetic patients, substantial epidemiological research on the likelihood of lumbar spinal stenosis diagnosis in individuals with diabetes is scarce.

Materials and methods: Using nationwide data, a total of 49,576 patients diagnosed with lumbar spinal stenosis based on ICD-10 codes were matched with controls of the same number based on age and sex. Employing a multivariable logistic regression model, the study assessed for the association between spinal stenosis and diabetes, while adjusting for confounders.

Results: We found a higher likelihood of lumbar spinal stenosis diagnosis in diabetic patients (OR 1.39, 95% CI 1.36 – 1.43, P<0.001). Those with HbA1c ≥7% and ≥1 diabetes-related complication also had an elevated likelihood (OR 1.19, 95% CI 1.08 - 1.31, P=0.001). Prolonged diabetes exposure increased the risk. Diabetes diagnosis reduced median survival by around 4.5 years for both stenosis and non-stenosis patients; spinal stenosis diagnosis alone minimally impacted survival. Relative to individuals diagnosed with diabetes mellitus (DM) at the age of 65 or older, the odds ratio (OR) for developing lumbar spinal stenosis (LSS) were 1.22 (95% CI 1.18 - 1.27, P<0.001) when DM was diagnosed at 50-65 years old and 1.67 (95% CI 1.56 - 1.79, P<0.001) for those under 50 years old. Multivariate analysis revealed a significantly increased risk of all-cause mortality in patients with DM and spinal stenosis (HR 1.36, 95% CI 1.29 - 1.44, P<0.001) and those with DM without stenosis (HR 1.49, 95% CI 1.41 - 1.57, P<0.001), compared to controls.

Diabetic patients with prolonged disease, poor glycemic control, and diabetes-related complications face an elevated risk of developing lumbar spinal stenosis. Recognizing the reciprocal adverse relationship between these conditions is crucial in clinical practice and designing public health measures for managing both conditions.

Level of evidence: 4.

The London Spine Unit : best situated treatment clinic in London

Read the original publication:

Diabetes Mellitus and Poor Glycemic Control are Associated with a Higher Risk of Lumbar Spinal Stenosis: An Analysis of a Large Nationwide Database

Related Posts

0/5 (0 Reviews)

Trusindex Reviews

London Spine Unit Harley Street Hospital

A Focus on High Quality Specialised Care

We are a specialist Private Hospital based on Harley Street, London UK The Harley Street Hospital, Day Surgery Hospital

We provide exclusive health services for individuals seeking Advanced medical, non-surgical or minimally invasive treatments. We are covered by All Insurance Companies apart from AXA PPP

Our Medical Director and Lead Spinal Surgeon Mr Mo Akmal MD is a world renowned Spine Specialist Consultant with over 20 years of experience. He and his team have developed revolutionary techniques to perform all types of Spinal Surgery as a Day Case procedure without traditional General Anaesthetic.

We are constantly improving our techniques for treatment and improving facilities for our patients.

Book your Appointment Now 
Check out our Reviews 
Check out our Patient Videos 
Check our Mr Akmal’s Profile

 

What our patients say ...

Abstract Study design: A large-scale retrospective case-control study. Objective: Examine diabetes as a risk factor for lumbar spinal stenosis development and evaluate the impact of diabetes duration, glycemic control, and associated complications on this risk. Summary of background data: Diabetes mellitus, a multiorgan disorder impacting various connective tissues, induces histological changes in spinal structures, particularly

Revolutionary Keyhole surgical technique to vaporise bulging discs

Dr Mo Akmal Medical Director
Dr Mo Akmal MD - Lead Spinal Surgeon

Laser Disc Surgery can be performed under local anaesthetic at The Harley Street Hospital.

Initial Consultation

with Consultant Spine Surgeon
£ 250
  • No Waiting Times
  • Top NHS affiliated Consultant
  • Includes Clinical Review and Report
  • Multidisciplinary discussion
  • Review of Previous Scans and Reports

Follow up Consultation

any appointment after initial consultation
£ 180
  • Top NHS affiliated Consultant
  • Includes Clinical Review and Report
  • Multidisciplinary discussion

High Resolution MRI Scan

any Single Region (3.0 Tesla)
£ 600
  • No waiting times
  • Includes Full Radiologist Report
  • Open or Closed MRI scan types
  • Copy of Scan on CD

Website Offer

Pre-Booked Online
£1130
£ 800
  • Initial Consultation
  • MRI Scan (Single Region)
  • Follow Up consultation
  • Same Day One Stop Visit
  • Full Medical and MRI scan Report
  • Copy of scan on CD
Popular

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810