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Development and in vivo biomechanics of goat mobile artificial lumbar spine complex – Lumbar Fusion

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The article discusses the development and testing of a mobile artificial lumbar complex (MALC) suitable for reconstruction after subtotal lumbar resection in goats. The study included 18 male boer goats divided into control, fusion, and non-fusion groups. The results showed that the MALC designed by 3D printing successfully restored intervertebral height while maintaining stability and motor function of the lumbar spine. Biomechanical testing revealed that the non-fusion group had similar range of motion (ROM) to the control group, while the fusion group had significantly reduced ROM. Overall, the study concludes that individual MALC can effectively restore intervertebral height and maintain stability in the lumbar spine

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most advanced sugical centre in London

Published article

: The individual MALC could restore intervertebral height of lumbar vertebra while maintaining the stability of lumbar vertebra and re-establishing motor function of lumbar space.

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Zhongguo Gu Shang. 2024 Mar 25;37(3):281-7. doi: 10.12200/j.issn.1003-0034.20221073.ABSTRACTOBJECTIVE: Mobile artificial lumbar complex (MALC) which suitable for reconstruction after subtotal lumbar resection in goats was developed,and to test stability of the complex and postoperative lumbar segmental motor function.METHODS: Eighteen male boer goats aged from 1 to 2 years old (weighted from 35 to 45 kg) were,

Zhongguo Gu Shang. 2024 Mar 25;37(3):281-7. doi: 10.12200/j.issn.1003-0034.20221073.

ABSTRACT

OBJECTIVE: Mobile artificial lumbar complex (MALC) which suitable for reconstruction after subtotal lumbar resection in goats was developed,and to test stability of the complex and postoperative lumbar segmental motor function.

METHODS: Eighteen male boer goats aged from 1 to 2 years old (weighted from 35 to 45 kg) were selected and divided into control group,fusion group and non-fusion group,with 6 goats in each group. According to preoperative CT scans and MRI examinations of lumbar,the goat MALC was designed and performed by 3D printed for non-fusion group. Operation was performed on three groups respectively,and only vertebral body and disc were exposed in control group. In fusion group,L4 part of vertebral body and the upper and lower complete disc tissues were removed,and the lumbar spine bone plate fixation was performed with titanium mesh bone grafting. In non-fusion group,vertebral body and disc were removed in the same way,and MALC was implanted. AP and lateral X-rays of lumbar vertebrae in goat were taken at 6 months after surgery,in order to understand whether the plant was dislocated,displaced and fractured. Biomechanical tests were performed on the specimens by mechanical instrument to measure range of motion (ROM) of L2,3,L3,4,L4,5 intervertebral space and the overall ROM of L2-5 lumbar vertebrae.

RESULTS: MALC of lumbar vertebra was designed by 3D printing,and its component artificial vertebrae and upper and lower artificial end plates were manufactured. The semi-spherical structure was fabricated by precision lathe using high-crosslinked polyethylene material,and the prosthesis was assembled. Postoperative AP and lateral X-rays of lumbar vertebra at 6 months showed the implant position of implant and MALC were good without displacement and dislocation. In vitro biomechanical test of lumbar vertebrae specimens:(1) There were no statistical significance in ROM of lumbar intervertebral space flexion and extension,lateral flexion and rotation on L3,4 and L4,5,between non-fusion group and control group (P>0.05),while ROM of fusion group was significantly reduced compared with the other two groups (P<0.05). There were no significant difference in ROM of L2,3 intervertebral flexion and extension,lateral flexion and rotation between non-fusion group and control group (P>0.05),while fusion group was significantly increased compared with the other two groups (P<0.001). (2) There was no significant difference in overall lumbar ROM of L2-5 (P> 0.05).

: The individual MALC could restore intervertebral height of lumbar vertebra while maintaining the stability of lumbar vertebra and re-establishing motor function of lumbar space.

PMID:38515416 | DOI:10.12200/j.issn.1003-0034.20221073

The London Spine Unit : most advanced sugical centre in London

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Development and in vivo biomechanics of goat mobile artificial lumbar spine complex

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Zhongguo Gu Shang. 2024 Mar 25;37(3):281-7. doi: 10.12200/j.issn.1003-0034.20221073.ABSTRACTOBJECTIVE: Mobile artificial lumbar complex (MALC) which suitable for reconstruction after subtotal lumbar resection in goats was developed,and to test stability of the complex and postoperative lumbar segmental motor function.METHODS: Eighteen male boer goats aged from 1 to 2 years old (weighted from 35 to 45 kg) were
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