Computed tomography shade mapping for analysis of bone ongrowth on the floor of a titanium-coated polyetheretherketone cage in vivo: A pilot research.
Medication (Baltimore). 2018 Sep;97(37):e12379
Authors: Makino T, Kaito T, Sakai Y, Takenaka S, Yoshikawa H
Bone ongrowth on the surfaces of titanium (Ti)-coated polyetheretherketone (PEEK) supplies has been demonstrated in animal fashions; nevertheless, whether or not this happens on the surfaces of Ti-coated PEEK cages in lumbar interbody fusion has not been demonstrated clinically in vivo. This potential observational research was aimed to develop and validate a computed tomography (CT) shade mapping primarily based on Hounsfield unit (HU) values for analysis of bone ongrowth on the surfaces of the Ti-coated PEEK cage after posterior lumbar interbody fusion (PLIF).Twenty-four consecutive sufferers (11 males and 13 ladies; imply age, 67.zero years; vary, 20-82 years) who underwent single- or 2-level PLIF since March 2015 had been included. Two Ti-coated PEEK cages had been inserted in all PLIF segments. From reconstructed sagittal planes from postoperative CT scans (inside 1 week and 6 months postoperatively), bone ongrowth on the surfaces of cage frames was evaluated by CT shade mapping. Inter- and intraobserver reliability of the evaluation of bone ongrowth by CT shade mapping was evaluated by Cohen’s kappa coefficient. The relation between CT shade mapping and HU values on the surfaces of cage frames was additionally analyzed.A complete of 248 surfaces of cage frames had been evaluated. Bone ongrowth was noticed in 134 of 248 surfaces (54.zero%) by CT shade mapping. Intraobserver reliability for the analysis of bone ongrowth was kappa?=?zero.831, and interobserver reliability was kappa?=?zero.713. The HU values within the native areas of curiosity (ROIs) on the surfaces of cage frames the place the postoperative bone ongrowth existed on CT shade mapping elevated considerably postoperatively (P?<?.001), and the median postoperative change fee of the HU values within the native ROIs was 22.four%.The evaluation of bone ongrowth on the surfaces of Ti-coated PEEK cages by CT shade mapping had sufficient inter- and intraobserver reliability, which was helpful particularly in detecting native improve in HU values on the surfaces of the cages. This methodology is a simple and visually understandable methodology for the evaluation of bone ongrowth within the bone-implant interface.
PMID: 30213002 [PubMed – in process]