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Comparison of Fusion, Subsidence, and Clinical Results Between 3D-Printed Porous Titanium Cage and Polyetheretherketone (PEEK) Cage in Posterior Lumbar Interbody Fusion: A Minimum of 2-years follow-up – Published Article

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A study published in World Neurosurgery compared the outcomes of using 3D-printed porous titanium (3DP-titanium) cages versus polyetheretherketone (PEEK) cages for posterior lumbar interbody fusion (PLIF). The study included 150 patients who underwent PLIF and were followed-up for more than 2 years. The results showed that the 3DP-titanium cages had a higher fusion rate at 1 year and 2 years compared to PEEK cages. The amount of subsidence and incidence of significant subsidence were not significantly different between the two materials. Back pain/leg pain visual analogue scale (VAS) and Owestry disability index (ODI) were also similar between the groups. The study concluded that the 3DP-titanium cage can be safely used for PLIF due to its higher fusion rate and stable construct

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Published article

CONCLUSION: The 3DP-titanium cage resulted in a higher fusion rate than the PEEK cage when applied for PLIF. The subsidence rate did not differ significantly between the two cage materials. Therefore, the 3DP-titanium cage can be safely applied for PLIF, considering its stable construct.

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World Neurosurg. 2023 Jul 5:S1878-8750(23)00915-4. doi: 10.1016/j.wneu.2023.06.132. Online ahead of print.ABSTRACTOBJECTIVES: Early osteointegration and reduced modulus of elasticity has been proven with 3D-printed porous titanium (3DP-titanium) cage used for posterior lumbar interbody fusion (PLIF). The present study was conducted to demonstrate fusion rate, subsidence, and clinical outcome of the 3DP-titanium cage in PLIF and to,

World Neurosurg. 2023 Jul 5:S1878-8750(23)00915-4. doi: 10.1016/j.wneu.2023.06.132. Online ahead of print.

ABSTRACT

OBJECTIVES: Early osteointegration and reduced modulus of elasticity has been proven with 3D-printed porous titanium (3DP-titanium) cage used for posterior lumbar interbody fusion (PLIF). The present study was conducted to demonstrate fusion rate, subsidence, and clinical outcome of the 3DP-titanium cage in PLIF and to compare its results with those of polyetheretherketone (PEEK) cage METHODS: A total of 150 patients who underwent 1-2 level PLIF and were followed-up for more than 2 years were retrospectively reviewed. Fusion rates, subsidence, segmental lordosis, back pain visual analogue scale (VAS), leg pain VAS, and Owestry disability index (ODI) were assessed.

RESULTS: Higher 1-year (3DP-titanium, 86.9%; PEEK, 67.7%; p=0.002) and 2-years (3DP-titanium, 92.9%; PEEK, 82.3%; p=0.037) fusion rate could be achieved with using 3DP-titanium cages for PLIF compared to PEEK cages. Amount of subsidence (3DP-titanium, 1.4±1.6mm; PEEK, 1.9±1.8mm; p=0.092) and incidence of significant subsidence (3DP-titanium, 17.9%; PEEK, 23.4%; p=0.389) was not significantly different between the two materials. Furthermore, back pain/leg pain VAS and ODI also was not significantly different between the two groups. In logistic regression analysis, cage material (p=0.027) showed significant association with fusion while number of levels fused (p=0.012) was associated with subsidence.

CONCLUSION: The 3DP-titanium cage resulted in a higher fusion rate than the PEEK cage when applied for PLIF. The subsidence rate did not differ significantly between the two cage materials. Therefore, the 3DP-titanium cage can be safely applied for PLIF, considering its stable construct.

PMID:37419312 | DOI:10.1016/j.wneu.2023.06.132

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Comparison of Fusion, Subsidence, and Clinical Results Between 3D-Printed Porous Titanium Cage and Polyetheretherketone (PEEK) Cage in Posterior Lumbar Interbody Fusion: A Minimum of 2-years follow-up

Sciatica My mother was in absolute agony for more than 3 months due to sciatica. It just came out of nowhere and took her out of action. From working full time she went straight to being bed bound and unable to carry out simplest of actions.The pain was 9/10 and she was bed bound for those three months. Multiple trips to A&E and GP and they wouldn't class it as an emergency therefore they wouldn't do anything about it other than upgrading the painkillers which did next to nothing for my mother. I couldn't bear to watch my mother sleeping on A&E bench in pain for 7 hours, just to be told by doctors that she wouldn't be kept in. I remember her joining her hands and begging the doctors to stop the pain which broke my heart. I then started doing research on google and London spine unit came up with Dr Mo AKMAL's profile and review. First meeting with Dr AKMAL was via ZOOM as my mother was bed bound. Dr AKMAL spoke to me and my mom and told us that this is nothing to worry about and that the pain would be 100% gone.Dr AKMAL assured us to visit the hospital so he could physically inspect my mother and give us the best solution. One trip to the london spine unit and Dr AKMAL advised us that the best solution would be to carry out Minimally invasive disectomy. Dr AKMAL advised that due to my mother being bed bound for a while, steroid injection might not give the result that my mother wishes. Dr AKMAL was very confident and showed us some videos from other patients who had gone through the same ordeal. The biggest thing i noticed between before and after was the smile on the patients face. Dr AKMAL was constantly assuring my mother throughout the meeting that he would take care of her pain and gave her 100% confidence that the result would be delivered.He promised her that she would be walking pain free the same day after the operation. Before the operation Dr GURUNG was consulted multiple times and he also was very helpful. Right after the surgery, as Dr AKMAL promised, my mother was walking and the biggest thing was that the pain was gone. My mother had forgotten to smile for three months and there i saw her smiling again. Dr AKMAL and Dr GURUNG gave us brilliant aftercare and informed us that just give them a ring if there was any issue. Its been several weeks now and my mother is heading towards complete recovery without any issues. The pain is completely gone and anyone who is reading this going through the same horrible sciatica pain you must come and see Dr AKMAL. Thank you Dr AKMAL and your whole team for helping my mom achieve this pain free life.

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World Neurosurg. 2023 Jul 5:S1878-8750(23)00915-4. doi: 10.1016/j.wneu.2023.06.132. Online ahead of print.ABSTRACTOBJECTIVES: Early osteointegration and reduced modulus of elasticity has been proven with 3D-printed porous titanium (3DP-titanium) cage used for posterior lumbar interbody fusion (PLIF). The present study was conducted to demonstrate fusion rate, subsidence, and clinical outcome of the 3DP-titanium cage in PLIF and to

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