19 Harley St, London, W1G 9QJ, UK
We are London's Top Spine Clinic

Comparability of 4 strategies for backbone stereotactic physique radiotherapy: Dosimetric and effectivity evaluation.

Icon for Wiley Icon for PubMed Central Related Articles

Comparability of 4 strategies for backbone stereotactic physique radiotherapy: Dosimetric and effectivity evaluation.

J Appl Clin Med Phys. 2018 Mar;19(2):160-167

Authors: Aljabab S, Vellayappan B, Vandervoort E, Bahm J, Zohr R, Sinclair J, Caudrelier JM, Szanto J, Malone S

PURPOSE: The goal of this examine is to check the dosimetric variations between 4 strategies for backbone stereotactic physique radiotherapy (SBRT): CyberKnife (CK), volumetric modulated arc remedy (VMAT), and helical tomotherapy (HT) with dynamic jaws (HT-D) and glued jaws (HT-F).
MATERIALS/METHODS: Information from 10 sufferers had been utilized. All sufferers had been deliberate for 24 Gy in two fractions, with the first aims being: (a) limiting the utmost dose to the wire to ? 17 Gy and/or cauda equina to ? 20 Gy, and (b) to maximise the medical goal quantity (CTV) to obtain the prescribed dose. Remedy plans had been generated by separate dosimetrists after which in contrast utilizing velocity AI. Parameters of comparability embrace goal quantity protection, conformity index (CI), gradient index (GI), homogeneity index (HI), remedy time (TT) per fraction, and monitor items (MU) per fraction.
RESULTS: PTV D2 and D5 had been considerably larger for CK in comparison with VMAT, HT-F, and HT-D (P < zero.001). The typical quantity of CTV receiving the prescription dose (CTV D95) was considerably much less for VMAT in comparison with CK, HT-F and HT-D (P = zero.036). CI improved for CK (zero.69), HT-F (zero.66), and HT-D (zero.67) in comparison with VMAT (zero.52) (P = zero.013). CK (41.86) had the biggest HI in comparison with VMAT (26.99), HT-F (20.69), and HT-D (21.17) (P < zero.001). GI was considerably much less for CK (three.96) in comparison with VMAT (6.76) (P = zero.001). Likewise, CK (62.four min, 14059 MU) had the longest remedy time and MU per fraction in comparison with VMAT (eight.5 min, 9764 MU), HT-F (13 min, 10822 MU), and HT-D (13.5 min, 11418 MU) (P < zero.001).
CONCLUSION: Each CK and HT plans achieved conformal goal protection whereas respecting wire tolerance. Dose heterogeneity was considerably bigger in CK. VMAT required the least remedy time and MU output, however had the least steep GI, CI, and goal protection.

PMID: 29417728 [PubMed – indexed for MEDLINE]

Share to care...

Share on facebook
Share on twitter
Share on pinterest
Share on google
Share on linkedin
Share on skype

What we do...

The Harley Street Hospital


What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

We treat all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say about us ......