The article presents a meta-analysis comparing the clinical efficacy and safety of Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) in patients with cervical degenerative disc diseases. The researchers conducted a search of multiple databases and included 8 randomized controlled trials in the analysis. The results indicate that while there was no significant difference in terms of NDI scores, VAS scores, EQ-5D scores, and dysphagia between the two groups, the DCDA group had a higher incidence of reoperation and a lower incidence of adjacent segment degeneration (ASD). In conclusion, DCDA and ACDF have similar outcomes in several aspects, but DCDA may reduce the risk of ASD while increasing the risk of reoperation
Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : top treatment hospital in UK
Published article
DCDA and ACDF have similar results in terms of NDI scores, VAS scores, EQ-5D scores, and dysphagia. In addition, DCDA can reduce the risk of ASD but increases the risk of reoperation.
Cervical Disc Arthroplasty Surgery Expert. Best Spinal Surgeon UK
Abstract Objective: This study aims to evaluate the clinical efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) in Cervical degenerative disc diseases. Methods: Two researchers independently conducted a search of PubMed, EMBASE, and Cochrane Central Register of Controlled Trails (CENTRAL) for randomized controlled trials (RCTs) following the,
Abstract
Objective: This study aims to evaluate the clinical efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) in Cervical degenerative disc diseases.
Methods: Two researchers independently conducted a search of PubMed, EMBASE, and Cochrane Central Register of Controlled Trails (CENTRAL) for randomized controlled trials (RCTs) following the Cochrane methodology guidelines. A fixed-effects or random-effects model was applied based on different heterogeneity. Review Manager (Version 5.4.1) software was used to perform data analysis.
Results: A total of 8 RCT studies were included in this meta-analysis. The results indicate that the DCDA group had a higher incidence of reoperation (P = 0.03) and a lower incidence of ASD (P = 0.04) than the CDA group. There was no significant difference between two groups regarding NDI score (P = 0.36), VAS ARM score (P = 0.73), VAS NECK score (P = 0.63), EQ-5D score (P = 0.61) and dysphagia incidence (0.18).
DCDA and ACDF have similar results in terms of NDI scores, VAS scores, EQ-5D scores, and dysphagia. In addition, DCDA can reduce the risk of ASD but increases the risk of reoperation.
Keywords: anterior cervical discectomy and fusion; degenerative disc diseases; discover cervical disc arthroplasty; meta-analysis; randomized controlled trial.
The London Spine Unit : top treatment hospital in UK
Read the original publication:
Comparison of discover cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical degenerative disc diseases: A meta-analysis of prospective, randomized controlled trials