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Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study – Lumbar Fusion

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This article is a retrospective cohort study comparing the effectiveness of autologous bone grafts and artificial bone grafts in lumbar lateral interbody fusion surgery. The study evaluated 15 cases and 34 intervertebral levels, comparing the bone fusion rates between Autogenous bone and Affinos® (artificial bone). The evaluation was done using computed tomography (CT) images in the coronal and sagittal planes. After one year, 70.8% of windows transplanted with autologous bones showed bone fusion, compared to 47.4% of windows transplanted with Affinos®. However, after two years, the bone fusion rates increased for both groups, with 79.2% of autologous bone windows and 79.0% of Affinos® windows showing bone fusion. The difference in fusion rates between the two groups was not statistically significant. The study suggests that Affinos® is a promising alternative to autologous bone grafts in lumbar lateral interbody fusion surgery

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : innovative day surgery hospital in London

Published article

This retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences between the artificial bone, Affinos^(®) (Kuraray Co., Tokyo, Japan), and autogenous bone. Two years post-surgery, we evaluated computed tomography (CT) multi-planar reconstruction images…

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Cureus. 2023 Sep 30;15(9):e46240. doi: 10.7759/cureus.46240. eCollection 2023 Sep.ABSTRACTThis retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences,

Cureus. 2023 Sep 30;15(9):e46240. doi: 10.7759/cureus.46240. eCollection 2023 Sep.

ABSTRACT

This retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences between the artificial bone, Affinos® (Kuraray Co., Tokyo, Japan), and autogenous bone. Two years post-surgery, we evaluated computed tomography (CT) multi-planar reconstruction images in the coronal and sagittal planes. One year after surgery, out of the 24 windows, 17 (70.8%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 18 (47.4%) windows transplanted with Affinos® showed bone fusion. Two years post-surgery, out of the 24 windows, 19 (79.2%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 30 (79.0%) windows transplanted with Affinos® showed bone fusion, and no difference was observed in the fusion rate at two years post-surgery (P = 0.238). In cases using Affinos® for transplanted bone, the bone fusion rate increased between one and two years. The rate of bony fusion using Affinos® in lateral lumbar interbody fusion (LLIF) cages is at par with that of autologous bone grafts at two years post-surgery. Affinos® is a promising candidate for graft material in LLIF surgery.

PMID:37908955 | PMC:PMC10614489 | DOI:10.7759/cureus.46240

The London Spine Unit : innovative day surgery hospital in London

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Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study

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Cureus. 2023 Sep 30;15(9):e46240. doi: 10.7759/cureus.46240. eCollection 2023 Sep.ABSTRACTThis retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences

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