Live Video Consultation
19 Harley St, London, W1G 9QJ, UK

Clinical results of lumbar total disc arthroplasty in accordance with Modic signs, with a 2-year-minimum follow-up

STUDY DESIGN: Prospective study. OBJECTIVE: The aim of this prospective study is to analyze the influence of Modic type on the clinical results of lumbar total disc arthroplasty. SUMMARY OF BACKGROUND DATA: Some patients with lumbar disc degeneration have endplate signal changes on magnetic resonance images, which have been classified by Modic. Modic-1 endplates changes are associated with an inflammatory phase of the disease whereas Modic-2 endplates changes correspond to a quiescent phase with a fatty replacement. The effect of Modic endplate changes on the clinical results of lumbar fusion has been studied by multiple authors, but the influence of Modic type on clinical outcomes of lumbar disc replacement is not known. METHODS: A total of 221 patients with a mean age of 42 years were included in this study. Of which, 107 patients were classified Modic 0, 65 Modic 1, and 49 Modic 2. Clinical evaluation (Oswestry Disability Index [ODI], lumbar and radicular pain using the Visual Analog Score [VAS]) was performed preoperatively and at 3, 6, 12, and 24 months minimum postoperatively. RESULTS: Mean follow-up was 30 months (24-72 months). Significant clinical improvement (P < 0.05) was observed in pain and ODI between the preoperative evaluation and final follow-up. Multivariate analysis between the 3 groups demonstrated a significant difference in Oswestry Disability Index (size of the effect was measured at -0.3 [-0.55-0.04]) and on the radicular pain (size of the effect was measured at -0.4 [-0.7-0.1]), with lower scores in the group classified Modic 1. CONCLUSION: Superior results were achieved in the group of patients with Modic-1 endplate changes on magnetic resonance images. These data may be helpful in patient selection and in preoperative patient counseling Keywords : Adolescent,Adult,Arthroplasty,classification,diagnosis,diagnostic imaging,Disability Evaluation,Female,Follow-Up Studies,Humans,Intervertebral Disc,Intervertebral Disc Degeneration,Lumbar Vertebrae,Magnetic Resonance Imaging,Male,methods,Middle Aged,Multivariate Analysis,Pain,Pain Measurement,Patient Selection,Prospective Studies,Radiography,surgery,Time Factors,Total Disc Replacement,Treatment Outcome,Young Adult,, Lumbar,Total,Disc, fibromyalgia specialist

Date of Publication : 2011 Dec 15

Authors : Blondel B;Tropiano P;Gaudart J;Huang RC;Marnay T;

Organisation : Orthopedic and Vertebral Department, Hopital Nord, Universite de la Mediterranee, Marseille, France. [email protected]

Journal of Publication : Spine (Phila Pa 1976 )

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21252824

The London Spine Unit : Harley Street UK. Specialists in Cutting Edge Technologies for Spinal Surgery

Make an Appointment 

Trustpilot Reviews
Doctify Reviews
Top Doctor Reviews

Clinical Results of Lumbar Total Disc Arthroplasty in Accordance with Modic Signs, with a 2 Year Minimum Follow-Up | Back specialist harley street

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810