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Scientific consequence comparability of polymethylmethacrylate bone cement with and with out mineralized collagen modification for osteoporotic vertebral compression fractures.

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Scientific consequence comparability of polymethylmethacrylate bone cement with and with out mineralized collagen modification for osteoporotic vertebral compression fractures.

Drugs (Baltimore). 2018 Sep;97(37):e12204

Authors: Wang X, Kou JM, Yue Y, Weng XS, Qiu ZY, Zhang XF

Summary
A retrospective research of consecutive sufferers.The aim of this research was to check the medical impact of biomimetic mineralized collagen (MC) modified polymethylmethacrylate (PMMA) bone cement and conventional PMMA bone cement for the remedy of osteoporotic vertebral compression fractures (OVCF).New fracture on adjoining degree is the main postoperative complication of percutaneous vertebroplasty (PVP). The medical incidence was 12.four% to 27.7%. The elevated stiffness of the handled vertebral physique attributable to filling bone cement is taken into account as one of many important causes.A complete of 30 sufferers handled with conventional PMMA bone cement from June 2013 to March 2016 have been chosen as the normal group, whereas 50 sufferers handled with MC modified PMMA bone cement from July 2014 to March 2016 have been chosen because the modified group. The two teams have been in contrast by injection time of the bone cements, postoperative ache aid results, vertebral peak restoration, CT worth adjustments of the handled vertebral our bodies, and postoperative issues within the medical observations.The surgical procedures have been efficiently accomplished in each teams. Within the remedy of OVCF, the MC modified bone cement was capable of obtain the identical ache aid and vertebral peak restoration results in comparison with conventional bone cement throughout the follow-ups, though the injection time of the cement was extended within the operation. MC modified bone cement considerably lowered the incidence of postoperative adjoining vertebral fracture from 13.three% to 2%, and considerably elevated bone density of the handled vertebral our bodies.The MC modified PMMA bone cement confirmed good medical outcomes and higher mechanical properties than the normal bone cements.

PMID: 30212950 [PubMed – in process]

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