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[Clinical comparison of polymethylmethacrylate and bone cement in the treatment of osteoporotic vertebral compression fractures: a retrospective study].

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[Clinical comparison of polymethylmethacrylate and bone cement in the treatment of osteoporotic vertebral compression fractures: a retrospective study].

Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Apr 18;49(2):267-273

Authors: Shang LP, Tian Y, Liu XG

Summary
OBJECTIVE: To research the outcomes of sufferers with osteoporotic vertebral compression fractures handled with polymethylmethacrylate (PMMA) and GeneX bone cement in percutaneous kyphoplasty and to offer steerage in choosing the vertebral filling materials for this process.
METHODS: On this examine, 86 sufferers with osteoporotic vertebral compression fractures handled at Peking College Third Hospital between June 2012 and June 2013 have been retrospectively analyzed. The sufferers have been followed-up with questionnaires and X-ray and CT examinations after 1 month, three months, 6 months, and 1 12 months. Postoperative situations, together with restoration fee of vertebral peak, restoration fee of vertebral Cobb angle, CT knowledge, reductions in visible analogue scale (VAS) and Oswestry scores, and postoperative issues, have been evaluated. The outcomes have been analyzed utilizing SPSS 18.zero.
RESULTS: In accordance with the rank sum check, there have been vital variations within the restoration fee of vertebral peak, vertebral Cobb angle and vertebral quantity between the 2 teams after three months, 6 months, and 1 12 months (P<zero.05). The GeneX group had better losses in vertebral peak, Cobb angle and quantity than did the PMMA group. The PMMA group had three circumstances of cement leakage and 1 case of an adjoining vertebral fracture after percutaneous kyphoplasty. The GeneX group had 2 circumstances of cement leakage.
CONCLUSION: GeneX bone cement is just like PMMA by way of postoperative ache aid. Because the filling materials in percutaneous kyphoplasty, it’s efficient at sustaining vertebral peak, rapidly improves power and stiffness of the vertebral physique and has fewer issues. Nevertheless, it’s not passable in sustaining long-term postoperative vertebral peak. GeneX bone cement can be utilized because the filling materials for sufferers with osteoporotic vertebral compression fractures in percutaneous kyphoplasty. Sufferers with extreme osteoporosis and vertebral compression needs to be handled with standardized osteoporosis remedy and will attempt to keep away from early postoperative strolling workouts. Sustained vertebral filling supplies, corresponding to PMMA, are extra appropriate for such sufferers. Analysis into higher biodegradable supplies remains to be wanted.

PMID: 28416837 [PubMed – indexed for MEDLINE]

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