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Characteristics, comorbidities, and complications in multiple sclerosis (MS) and non-MS patients undergoing lumbar fusion for deformity – Lumbar Fusion

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This article examines the characteristics, comorbidities, and complications of patients with spinal deformity undergoing primary lumbar spine fusion, specifically comparing those with and without multiple sclerosis (MS). The study used data from the Nationwide Inpatient Sample and analyzed the medical records of 842 MS patients and 165,726 non-MS patients. The findings showed that MS patients undergoing spinal fusion were generally younger, more likely to be female, and more likely to have surgery at urban teaching hospitals. They also had higher rates of depression but lower rates of diabetes, hypertension, and renal failure compared to non-MS patients. However, there were no significant differences in mortality or perioperative complication rates between the two groups

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
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Published article

CONCLUSION: We found that MS versus non-MS patients undergoing primary lumbar fusion for spinal deformity were younger, more likely to be female and had higher rates of depression but lower rates of diabetes, hypertension, and renal failure. Notably, both groups experienced comparable mortality and perioperative complication rates.

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Surg Neurol Int. 2023 Jul 14;14:247. doi: 10.25259/SNI_506_2023. eCollection 2023.ABSTRACTBACKGROUND: We compared the characteristics, comorbidities, and complications in spinal deformity patients with and without multiple sclerosis (MS) undergoing primary lumbar spine fusion.METHODS: We used the Nationwide Inpatient Sample (NIS) from 2003 to 2014, International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure codes,

Surg Neurol Int. 2023 Jul 14;14:247. doi: 10.25259/SNI_506_2023. eCollection 2023.

ABSTRACT

BACKGROUND: We compared the characteristics, comorbidities, and complications in spinal deformity patients with and without multiple sclerosis (MS) undergoing primary lumbar spine fusion.

METHODS: We used the Nationwide Inpatient Sample (NIS) from 2003 to 2014, International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure codes to create experimental MS (842 patients) and non-MS control (165,726 patients) cohorts undergoing primary lumbar spine fusion. Characteristics, comorbidities, and complications in spinal deformity patients with and without MS were evaluated using univariate and bivariate analysis.

RESULTS: MS spinal deformity patients undergoing primary lumbar spine fusion were younger, more likely to be female and more likely to undergo surgery at urban teaching hospitals. They also exhibited higher rates of depression and lower rates of diabetes without chronic complications, hypertension, and renal failure. However, no significant differences were found in mortality or total perioperative complication rates between MS and nonMS patients.

CONCLUSION: We found that MS versus non-MS patients undergoing primary lumbar fusion for spinal deformity were younger, more likely to be female and had higher rates of depression but lower rates of diabetes, hypertension, and renal failure. Notably, both groups experienced comparable mortality and perioperative complication rates.

PMID:37560582 | PMC:PMC10408649 | DOI:10.25259/SNI_506_2023

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Characteristics, comorbidities, and complications in multiple sclerosis (MS) and non-MS patients undergoing lumbar fusion for deformity

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Surg Neurol Int. 2023 Jul 14;14:247. doi: 10.25259/SNI_506_2023. eCollection 2023.ABSTRACTBACKGROUND: We compared the characteristics, comorbidities, and complications in spinal deformity patients with and without multiple sclerosis (MS) undergoing primary lumbar spine fusion.METHODS: We used the Nationwide Inpatient Sample (NIS) from 2003 to 2014, International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure codes

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