Cervical backbone fractures in osteopetrosis: a case report and evaluation of the literature.
J Biomed Res. 2018 Jan 18;32(1):68-76
Authors: Ahmadpour A, Goodarzi A, Lee DJ, Panchal RR, Kim KD
Whereas administration of appendicular fractures has been effectively described within the setting of osteopetrosis, there may be restricted data on managing fractures of the axial backbone. Right here we current an osteopetrotic affected person with a number of traumatic a number of, comminuted, unstable cervical spinal fractures managed with non-operative stabilization, and supply a evaluation of the pathophysiology, genetic traits, and particular concerns that should be explored when figuring out operative versus non-operative administration of spinal damage in osteopetrosis. A PubMed question was carried out for English articles within the literature revealed as much as June 2016, and used the next search phrases alone and together: “osteopetrosis”, “backbone”, “fractures”, “osteoclasts”, and “operative administration”. Inside 4 months after preliminary damage, remedy with halo vest allowed for sufficient therapeutic. The affected person was asymptomatic with cervical backbone dynamic radiographs confirming stability at 4 months. On four-year comply with up examination, the affected person remained with out neck ache, and CT scan demonstrated partially sclerotic fracture strains with applicable anatomical alignment. In conclusion, exterior halo stabilization could also be an efficient choice for remedy of a number of unstable acute traumatic cervical backbone fractures in sufferers with osteopetrosis. Given the problem of surgical stabilization in osteopetrosis, additional analysis is critical to elucidate the optimum type of remedy on this choose affected person inhabitants.
PMID: 29353820 [PubMed]