19 Harley St, London, W1G 9QJ, UK

Cervical epidural plasmacytoma presenting as ascending paraparesis

BACKGROUND CONTEXT: Spinal epidural plasmacytomas are very rare and are usually localized in the cervicothoracic and lumbar spines. PURPOSE: To present the first case of cervical dural plasmacytoma and discuss the treatment options for this entity. STUDY DESIGN: Case report and review of the literature. METHODS: A 45-year-old man presented with gradually progressive legs to arms numbness preceded by upper respiratory tract infection and followed by rapid flaccid quadriparesis over 1 week. Because of the above symptoms, he was initially thought to have Guillain-Barre syndrome, but this diagnosis was ruled out by an emergency normal nerve conduction studies and needle electromyography. Cervical magnetic resonance imaging revealed an enhancing epidural mass at the C4-C7 level on T1-weighted images and increased signal on T2, causing spinal cord compression. Complete surgical evacuation was performed. Subsequent histology revealed plasmacytoma associated with anaplastic multiple myeloma, and the patient was referred to the hematology department for further treatment. RESULTS: Follow-up at 9 and 13 months after surgery revealed complete remission of the primary disease (multiple myeloma). The patient was neurologically improved and ambulatory with unilateral support. CONCLUSION: The reported case describes the first epidural extramedullary plasmacytoma isolated in the cervical spine in the English literature. Emergent neuroimaging and surgery can dramatically affect prognosis of this rare spinal neoplasm

Keywords : Affect,Arm,Cervical Vertebrae,complications,diagnosis,Diagnosis,Differential,Electromyography,Epidural Neoplasms,etiology,Humans,Infection,Leg,Magnetic Resonance Imaging,Male,methods,Middle Aged,Multiple Myeloma,Paraparesis,pathology,Plasmacytoma,Prognosis,Remission Induction,Spinal Cord,Spinal Cord Compression,Spine,surgery,Syndrome,Universities,, Epidural,Plasmacytoma,Presenting,As,Ascending, radio frequency surgery

Date of Publication : 2011 May

Authors : Lourbopoulos A;Ioannidis P;Balogiannis I;Stavrinou P;Koletsa T;Karacostas D;

Organisation : B’ Department of Neurology, AHEPA University Hospital, Stilponos Kyriakides 1 Street, Thessaloniki, Greece

Journal of Publication : Spine J

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21498133

The London Spine Unit : Harley Street UK. Specialists in Cutting Edge Technologies for Spinal Surgery

Make an Appointment 

Trustpilot Reviews
Doctify Reviews
Top Doctor Reviews

Cervical epidural plasmacytoma presenting as ascending paraparesis | Ibs groin pain symptoms

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810