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Candida lusitaniae discitis after discogram in an immunocompetent patient

BACKGROUND CONTEXT: Discitis or epidural abscess after discogram is a rare but known complication. It is more commonly bacterial; however, fungal discitis has been previously reported in immunocompromised patients. The management of fungal discitis in immunocompetent patients is rarely presented or addressed in the literature. PURPOSE: To present a rare atypical fungal discitis after routine discogram with a typical presentation in an immunocompetent host, review diagnostic and management guidelines for discitis, and provide recommendations for management of atypical discitis in immunocompetent patients. STUDY DESIGN: Case report and review of the literature. METHODS: A 40-year-old woman presented with a 3-week history of progressively worsening low back pain after a lumbar discogram. Magnetic resonance imaging revealed L3-L4 discitis without an epidural abscess. Left L3 and L4 hemilaminectomies with L3-L4 discectomy were performed. An inflammatory mass was seen in the L3-L4 disc space region extending to the left L3 foramen. RESULTS: Culture specimens obtained during surgery from both the disc and epidural space speciated to Candida lusitaniae. The patient completed a 6-month course of fluconazole therapy. At 2-year follow-up, she continued to be asymptomatic, without any recurrence of infection or neurologic sequelae. CONCLUSIONS: We report a case of C. lusitaniae spondylodiscitis after discography in an immunocompetent patient with long-term follow-up. Clinicians must maintain a high index of suspicion for discitis in patients who undergo this procedure. If discitis is suspected, culture specimens must be evaluated for fungal and mycobacterial organisms, even in the immunocompetent host. With proper surveillance, surgical intervention, and appropriate postoperative follow-up, this complication can be effectively managed with excellent long-term outcome

Keywords : Abscess,Antifungal Agents,Back,Back Pain,Candida,Candidiasis,Culture,diagnosis,Discitis,drug therapy,Epidural Abscess,Epidural Space,etiology,Female,Fluconazole,history,Humans,Immunocompetence,Infection,isolation & purification,Low Back Pain,Magnetic Resonance Imaging,methods,microbiology,Myelography,Pain,Patients,Recurrence,surgery,therapeutic use,therapy,Universities,, Lusitaniae,Discitis,After,Discogram, xyrem fibromyalgia uk

Date of Publication : 2011 Oct

Authors : Werner BC;Hogan MV;Shen FH;

Organisation : Department of Orthopaedic Surgery, University of Virginia Health System, 400 Ray C. Hunt, Charlottesville, VA 22908, USA

Journal of Publication : Spine J

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/22005083

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