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Brain and spinal cord haemorrhages associated with Angiostrongylus vasorum infection in four dogs

Multifocal haemorrhages associated with Angiostrongylus vasorum infection were observed in the central nervous system of four dogs with neurological signs including depression, seizures, spinal pain and paresis. In magnetic resonance images the majority of the lesions were isointense or slightly hyperintense in T1-weighted images, hyperintense in T2-weighted images and hypointense in T2*-weighted (gradient echo) images, compatible with haemorrhages more than seven days old. Lesions were found in the brain of three of the dogs and in the spinal cord of two. The cerebrospinal fluid contained high concentrations of protein and evidence of erythrophagia. All the dogs had coagulopathy and pulmonary haemorrhage of varying severity. A vasorum larvae were detected in the faeces of each of the dogs. Neural A vasorum was confirmed at postmortem examination in two dogs

Keywords : Angiostrongylus,Animals,Bleeding Time,Blood Cell Count,Brain,Brain Diseases,Central Nervous System,cerebrospinal fluid,complications,diagnostic imaging,Dog Diseases,Dogs,etiology,Fatal Outcome,Hemorrhage,Infection,Lethargy,Magnetic Resonance Imaging,Male,Myelography,Pain,parasitology,pathogenicity,Purpura,Respiratory Distress Syndrome,Adult,Seizures,Spinal Cord,Spinal Cord Diseases,Strongylida Infections,veterinary,, Spinal,Cord,Haemorrhages,Associated, botox injections into shoulder

Date of Publication : 2006 Jun 24

Authors : Wessmann A;Lu D;Lamb CR;Smyth B;Mantis P;Chandler K;Boag A;Cherubini GB;Cappello R;

Organisation : Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA

Journal of Publication : Vet Rec

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/16798954

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