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Greatest practices for the administration of local-regional recurrent chordoma: a place paper by the Chordoma World Consensus Group.

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Greatest practices for the administration of local-regional recurrent chordoma: a place paper by the Chordoma World Consensus Group.

Ann Oncol. 2017 Jun 01;28(6):1230-1242

Authors: Stacchiotti S, Gronchi A, Fossati P, Akiyama T, Alapetite C, Baumann M, Blay JY, Bolle S, Boriani S, Bruzzi P, Capanna R, Caraceni A, Casadei R, Colia V, Debus J, Delaney T, Desai A, Dileo P, Dijkstra S, Doglietto F, Flanagan A, Froelich S, Gardner PA, Gelderblom H, Gokaslan ZL, Haas R, Heery C, Hindi N, Hohenberger P, Hornicek F, Imai R, Jeys L, Jones RL, Kasper B, Kawai A, Krengli M, Leithner A, Logowska I, Martin Broto J, Mazzatenta D, Morosi C, Nicolai P, Norum OJ, Patel S, Penel N, Picci P, Pilotti S, Radaelli S, Ricchini F, Rutkowski P, Scheipl S, Sen C, Tamborini E, Thornton KA, Timmermann B, Torri V, Tunn PU, Uhl M, Yamada Y, Weber DC, Vanel D, Varga PP, Vleggeert-Lankamp CLA, Casali PG, Sommer J

Chordomas are uncommon, malignant bone tumors of the skull-base and axial skeleton. Till lately, there was no consensus amongst consultants relating to applicable medical administration of chordoma, leading to inconsistent care and suboptimal outcomes for a lot of sufferers. To handle this shortcoming, the European Society of Medical Oncology (ESMO) and the Chordoma Basis, the worldwide chordoma affected person advocacy group, convened a multi-disciplinary group of chordoma specialists to outline by consensus evidence-based greatest practices for the optimum method to chordoma. In January 2015, the primary suggestions of this group have been printed, protecting the administration of main and metastatic chordomas. Further proof and additional dialogue have been wanted to develop suggestions concerning the administration of local-regional failures. Thus, ESMO and CF convened a second consensus group assembly in November 2015 to deal with the remedy of regionally relapsed chordoma. This assembly concerned over 60 specialists from Europe, the USA and Japan with experience in remedy of sufferers with chordoma. The consensus achieved throughout that assembly is the topic of the current publication and enhances the suggestions of the primary place paper.

PMID: 28184416 [PubMed – indexed for MEDLINE]

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