. 2016 Sep;27(9):2823-2834.
Epub 2016 Apr 27.
G Zhao et al.
The study investigated whether kyphoplasty (KP) was superior to vertebroplasty (VP) in treating patients with osteoporotic vertebral compression fractures (OVCFs). KP may be superior to VP for treating patients with OVCFs based on long-term VAS and ODI but not short-term VAS. Further large-scale trials are needed to verify these findings due to potential risk of selection bias.
This study aimed to assess whether KP was superior to VP in treating patients with OVCFs.
The Medline, Embase, and Cochrane databases and references within articles and proceedings of major meetings were systematically searched. Eligible studies included patients with OVCFs who received either KP or VP. Standard mean differences (SMDs) and relative risks (RRs) were used as measures of efficacy and safety in a random-effects model.
Eleven studies enrolling 869 patients with OVCFs were identified as eligible for final analysis. Compared with VP, KP was associated with significant improvements in long-term (SMD, -0.70; 95 % confidence interval [CI]: -1.30, -0.10; P = 0.023) visual analog scale (VAS); short-term (SMD, -1.50; 95 % CI: -2.94, -0.07; P = 0.040) and long-term (SMD, -1.03; 95 % CI: -1.88, -0.18; P = 0.017) Oswestry Disability Indexes (ODIs); short-term (SMD, -0.74; 95 % CI: -1.42, -0.06; P = 0.032) and long-term (SMD, -0.71; 95 % CI: -1.19, -0.23; P = 0.004) kyphosis angles; and vertebral body height (SMD, 1.56; 95 % CI: 0.62, 2.49; P = 0.001) and anterior vertebral body height (SMD, 3.04; 95 % CI: 0.53, 5.56; P = 0.018). KP was also associated with a significantly longer operation time (SMD, 0.73; 95 % CI: 0.26, 1.19; P = 0.002) and a lower risk of cement extravasation (RR, 0.68; 95 % CI: 0.48, 0.96; P = 0.030) compared with VP. No significant differences were found in the short-term VAS, posterior vertebral body height, and adjacent-level fractures.
Acknowledging some risk of selection bias, KP displayed a significantly better performance compared with VP only in one of the two primary endpoints, that is, for ODI but not for short-term VAS. Further randomized studies are required to confirm these results.
Kyphoplasty; Meta-analysis; Osteoporotic vertebral compression fractures; Vertebroplasty.
Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis.
Ma XL, Xing D, Ma JX, Xu WG, Wang J, Chen Y.
Ma XL, et al.
Eur Spine J. 2012 Sep;21(9):1844-59. doi: 10.1007/s00586-012-2441-6. Epub 2012 Jul 26.
Eur Spine J. 2012.
Free PMC article.
Can Unilateral Kyphoplasty Replace Bilateral Kyphoplasty in Treatment of Osteoporotic Vertebral Compression Fractures? A Systematic Review and Meta-analysis.
Sun H, Lu PP, Liu YJ, Yang X, Zhou PH, Shen XF, Sun SW, Yang H.
Sun H, et al.
Pain Physician. 2016 Nov-Dec;19(8):551-563.
Pain Physician. 2016.
Balloon kyphoplasty versus percutaneous vertebroplasty for osteoporotic vertebral compression fracture: a meta-analysis and systematic review.
Wang B, Zhao CP, Song LX, Zhu L.
Wang B, et al.
J Orthop Surg Res. 2018 Oct 22;13(1):264. doi: 10.1186/s13018-018-0952-5.
J Orthop Surg Res. 2018.
Free PMC article.
A meta-analysis of balloon kyphoplasty compared to percutaneous vertebroplasty for treating osteoporotic vertebral compression fractures.
Xing D, Ma JX, Ma XL, Wang J, Xu WG, Chen Y, Song DH.
Xing D, et al.
J Clin Neurosci. 2013 Jun;20(6):795-803. doi: 10.1016/j.jocn.2012.05.038. Epub 2013 Feb 18.
J Clin Neurosci. 2013.
Early cement augmentation may be a good treatment option for pain relief for osteoporotic compression fractures: a systematic review and meta-analysis.
Seah SJ, Yeo MH, Tan JH, Hey HWD.
Seah SJ, et al.
Eur Spine J. 2023 Mar 25. doi: 10.1007/s00586-023-07658-9. Online ahead of print.
Eur Spine J. 2023.
Read more from the original source:
Balloon kyphoplasty versus percutaneous vertebroplasty for treatment of osteoporotic vertebral compression fractures (OVCFs) – PubMed
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Review . 2016 Sep;27(9):2823-2834. doi: 10.1007/s00198-016-3610-y. Epub 2016 Apr 27. Affiliations Affiliations 1 Department of Orthopedics, the Beijing Army General Hospital, No. 5, Nanmengcang Lane, Beijing, 100700, People’s Republic of China. email@example.com. 2 Department of Orthopedics, the Beijing Army General Hospital, No. 5, Nanmengcang Lane, Beijing, 100700, People’s Republic of China. PMID: 27121344 DOI: 10.1007/s00198-016-3610-y…
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