Live Video Consultation
19 Harley St, London, W1G 9QJ, UK

Atypical Teratoid/Rhabdoid Tumor of the Spinal Wire in a Little one: Case Report and Complete Evaluation of the Literature.

Related Articles

Atypical Teratoid/Rhabdoid Tumor of the Spinal Wire in a Little one: Case Report and Complete Evaluation of the Literature.

Pediatr Neurosurg. 2018 Might 22;:1-9

Authors: Babgi M, Samkari A, Al-Mehdar A, Abdullah S

Summary
INTRODUCTION: Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system is characterised by SMARCB1/INI deletion or mutation within the lengthy arm of chromosome 22 11(22q11.2), additionally leading to lack of nuclear expression of INI1 protein immunohistochemically. AT/RT tumors often happen in kids under three years. The tumor is often seen within the cerebellum or the cerebrum, with a particularly uncommon incidence within the spinal twine.
MATERIALS AND METHODS: We report a uncommon case of AT/RT in a 6-year-old boy who had a main spinal twine lesion within the thoracolumbar junction. Pathology revealed lack of nuclear staining of INI1 immunohistochemically. That is the primary case reported with combined intraspinal lesion (intra- and extramedullary). The affected person underwent two surgical procedures and acquired radiotherapy and chemotherapy; nonetheless, he died 16 months after the preliminary presentation.
RESULTS AND DISCUSSION: We reviewed the literature on all kids with spinal twine AT/RT. The evaluate confirmed that the cervical area is the commonest location of origin, particularly in youthful kids. Reported instances had been handled with a mixture of surgical procedure, systemic and intrathecal chemotherapy, and radiation remedy, and a survival time of 18 months represented the perfect end result. General imply survival time was 10 months.

PMID: 29788028 [PubMed – as supplied by publisher]

Atypical Teratoid/Rhabdoid Tumor of the Spinal Wire in a Little one Case Report and Complete Evaluation of the Literature | Neck pain specialist london

What our patients say ...

Consultant Spine Surgeon
Consultant Spine Surgeon
Consultant Spine Surgeon

This surgical technique consists of a percutaneous approach for the treatment of small to medium size hernias of the intervertebral disc by laser energy. The main objective is to reduce the intradiscal pressure in the nucleus pulposus

Laser Disc Surgery can be performed under local anaesthetic as a day case at our centre on the prestigious Harley Street.
What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

treatment of all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

If you have any emergency Doctor’s need, simply call our 24 hour emergency

Your personal case manager will ensure that you receive the best possible care.

Call Now 

+44 844 589 2020
+44 203 973 8810