Menu
Menu
19 Harley St, London, W1G 9QJ, UK
We are London's Top Spine Clinic

Atypical Teratoid/Rhabdoid Tumor of the Spinal Wire in a Little one: Case Report and Complete Evaluation of the Literature.

Related Articles

Atypical Teratoid/Rhabdoid Tumor of the Spinal Wire in a Little one: Case Report and Complete Evaluation of the Literature.

Pediatr Neurosurg. 2018 Might 22;:1-9

Authors: Babgi M, Samkari A, Al-Mehdar A, Abdullah S

Summary
INTRODUCTION: Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system is characterised by SMARCB1/INI deletion or mutation within the lengthy arm of chromosome 22 11(22q11.2), additionally leading to lack of nuclear expression of INI1 protein immunohistochemically. AT/RT tumors often happen in kids under three years. The tumor is often seen within the cerebellum or the cerebrum, with a particularly uncommon incidence within the spinal twine.
MATERIALS AND METHODS: We report a uncommon case of AT/RT in a 6-year-old boy who had a main spinal twine lesion within the thoracolumbar junction. Pathology revealed lack of nuclear staining of INI1 immunohistochemically. That is the primary case reported with combined intraspinal lesion (intra- and extramedullary). The affected person underwent two surgical procedures and acquired radiotherapy and chemotherapy; nonetheless, he died 16 months after the preliminary presentation.
RESULTS AND DISCUSSION: We reviewed the literature on all kids with spinal twine AT/RT. The evaluate confirmed that the cervical area is the commonest location of origin, particularly in youthful kids. Reported instances had been handled with a mixture of surgical procedure, systemic and intrathecal chemotherapy, and radiation remedy, and a survival time of 18 months represented the perfect end result. General imply survival time was 10 months.

PMID: 29788028 [PubMed – as supplied by publisher]

Share to care...

Share on facebook
Facebook
Share on twitter
Twitter
Share on pinterest
Pinterest
Share on google
Google+
Share on linkedin
LinkedIn
Share on skype
Skype

What we do...

The Harley Street Hospital

Testimonials

What is London spine unit and How it Works

The London Spine Unit was established in 2005 and has successfully treated over 5000 patients. All conditions are treated.

We treat all spinal disorders

The London Spine Unit specialises in Minimally Invasive Treatments allowing rapid recovery and return to normal function

Trusted by patients worldwide

The London Spine Unit provides the highest quality care to all patients and has VIP services for those seeking exceptional services

What our patients say about us ......