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Associations Between Visceral Fat Chronic Low Back Pain And Central Sensitization In Patients With Lumbar Spinal Stenosis London Spine

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Published article

CONCLUSIONS: Visceral fat is associated with CLBP, regardless of sex or age, and may be a potential therapeutic target for CLBP with CS.
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Abstract

Background: Pain sensitization may be one of the mechanisms contributing to chronic low back pain (CLBP).

Objective: To evaluate the association between visceral fat, CLBP, and central sensitization (CS); describe the relationship between low back pain (LBP) intensity and CS; and identify possible correlation between visceral fat and LBP intensity.

Methods: Patients with CLBP were divided using their CS inventory (CSI) scores into low- (CSI < 40) and high-CSI (CSI ⩾ 40) subgroups. We compared computed tomography (CT) measurements and scores for association with pain according to the visual analogue scale (VAS) between the two groups.

Results: The low-CSI and the high-CSI groups had 47 patients (67.1%; 21 men, 26 women) and 23 patients (32.9%; 11 men and 12 women), respectively. The high-CSI group had a significantly higher mean VAS score (p< 0.01) and estimated mean visceral fat area (p< 0.05) than the low-CSI group. There was a moderate positive correlation between VAS score and visceral fat (standardised partial regression coefficient: 0.659, p< 0.01) in the high-CSI group according to multiple linear regression analysis adjusted for age and sex.

Conclusions: Visceral fat is associated with CLBP, regardless of sex or age, and may be a potential therapeutic target for CLBP with CS.

Keywords: Chronic pain; central sensitization; central sensitization inventory; low back pain; visceral fat.

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Associations between visceral fat chronic low back pain and central sensitization in patients with lumbar spinal stenosis

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Abstract Background: Pain sensitization may be one of the mechanisms contributing to chronic low back pain (CLBP). Objective: To evaluate the association between visceral fat, CLBP, and central sensitization (CS); describe the relationship between low back pain (LBP) intensity and CS; and identify possible correlation between visceral fat and LBP intensity. Methods: Patients with CLBP…

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