Are metals concerned in tattoo-related hypersensitivity reactions? A case report.
Contact Dermatitis. 2017 Dec;77(6):397-405
Authors: de Cuyper C, Lodewick E, Schreiver I, Hesse B, Seim C, Castillo-Michel H, Laux P, Luch A
BACKGROUND: Allergic reactions to tattoos will not be unusual. Nevertheless, identification of the wrongdoer allergen(s) stays difficult.
OBJECTIVES: We current a affected person with papulo-nodular infiltration of 20-year-old tattoos related to systemic signs that disappeared inside per week after surgical elimination of metallic osteosynthesis implants from his backbone. We aimed to discover the causal relationship between the metallic implants and the affected person’s medical presentation.
METHODS: Metallic implants and a pores and skin biopsy of a reactive tattoo had been analysed for elemental contents by inductively coupled plasma mass spectrometry and synchrotron-based X-ray fluorescence (XRF) spectroscopy.
RESULTS: Nickel (Ni) and chromium (Cr) in addition to excessive ranges of titanium (Ti) and aluminium had been detected in each the pores and skin biopsy and the implants. XRF analyses recognized Cr(III), with Cr(VI) being absent. Patch testing gave damaging outcomes for Ni and Cr. Nevertheless, patch exams with an extract of the implants and metallic Ti on the tattooed pores and skin evoked flare-up of the signs.
CONCLUSION: The affected person’s hypersensitivity response and its spontaneous remission after elimination of the implants point out that Ti, probably together with among the different metals detected, may have performed a serious function on this specific case of tattoo-related allergy.
PMID: 28795428 [PubMed – indexed for MEDLINE]