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Anaphylaxis secondary to levobupivacaine

We describe the case of a 25-year-old woman presented for elective lumbar decompression and microdiscectomy who, towards the end of her surgery, developed clinical signs of anaphylaxis. Skin testing later confirmed sensitisation to levobupivacaine and possibly MediShield, an anti-adhesion gel used following microdiscectomy. This case is the first confirmed case report of anaphylaxis in response to levobupivacaine. It also highlights the possibility that multiple agents may simultaneously trigger a life-threatening reaction. Anaesthetists should remain alert to the use of potentially allergenic agents employed by surgeons

Keywords : Adult,adverse effects,analogs & derivatives,Anaphylaxis,Anesthesia,General,Anesthetics,Local,blood,Bupivacaine,Decompression,Surgical,Diskectomy,Drug Hypersensitivity,drug therapy,Elective Surgical Procedures,etiology,Female,Humans,Intubation,Intratracheal,Levobupivacaine,secondary,Skin,Skin Tests,surgery,therapy,Tryptases,, Secondary,Levobupivacaine, the back pain centre london

Date of Publication : 2011 Oct

Authors : Gupta A;Fennelly M;Ramesh V;Agyare K;

Organisation : Royal Marsden Hospital, London, UK. anish147@gmail.com

Journal of Publication : Anaesthesia

Pubmed Link : https://www.ncbi.nlm.nih.gov/pubmed/21770908

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