Evaluation of radiological parameters related to decreased fractional anisotropy values on diffusion tensor imaging in sufferers with lumbar spinal stenosis.
Eur Backbone J. 2018 Apr 26;:
Authors: Wang X, Wang H, Solar C, Zhou S, Meng T, Lv F, Ma X, Xia X, Jiang J
PURPOSE: Earlier research have indicated that decreased fractional anisotropy (FA) values on diffusion tensor imaging (DTI) are nicely correlated with the signs of nerve root compression. The intention of our research is to find out major radiological parameters related to decreased FA values in sufferers with lumbar spinal stenosis involving single L5 nerve root.
METHODS: Sufferers confirmed with single L5 nerve root compression by transforaminal nerve root blocks have been included on this research. FA values of L5 nerve roots on each symptomatic and asymptomatic aspect have been obtained. Standard radiological parameters, resembling disc top, degenerative scoliosis, dural sac cross-sectional space (DSCSA), foraminal top (FH), hypertrophic aspect joint degeneration (HFJD), sagittal rotation (SR), sedimentation signal, sagittal translation and traction spur have been measured. Correlation and regression analyses have been carried out between the radiological parameters and FA values of the symptomatic L5 nerve roots. A predictive regression equation was established.
RESULTS: Twenty-one sufferers have been included on this research. FA values have been considerably decrease on the symptomatic aspect evaluating to the asymptomatic aspect (zero.263?±?zero.069 vs. zero.334?±?zero.080, P?=?zero.038). DSCSA, FH, HFJD, and SR have been considerably correlated with the decreased FA values, with r?=?zero.518, zero.443, zero.472 and – zero.910, respectively (P?<?zero.05). DSCSA and SR have been discovered to be the first radiological parameters associated to the decreased FA values, and the regression equation is FA?=?- zero.012 × SR?+?zero.002 × DSCSA.
CONCLUSIONS: DSCSA and SR have been major contributors to decreased FA values in LSS sufferers involving single L5 nerve root, indicating that central canal decompression and segmental stability must be the primary issues in preoperative planning of those sufferers. These slides could be retrieved underneath Digital Supplementary Materials.
PMID: 29700619 [PubMed – as supplied by publisher]