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Analysis of Personalized Interbody Implants in the Surgical Treatment of Adult Spinal Deformity – Lumbar Fusion

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This article discusses a study on the use of personalized interbody spacers in adult spinal deformity (ASD) surgery. The International Spine Study Group (ISSG) found that surgeons often failed to achieve alignment goals in complex adult deformity surgery (CADS) cases. The study aimed to determine if personalized interbody spacers could lead to better alignment outcomes. The results showed that utilizing personalized interbodies improved the achievement of goal segmental sagittal and coronal alignment, as well as goal pelvic incidence-to-lumbar lordosis mismatch (PI-LL), compared to stock devices. This study supports the use of personalized interbodies to enhance alignment goals in ASD surgery

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : best recognised day surgery hospital in the world

Published article

S: This study supports use of personalized interbodies as a means of better achieving goal segmental sagittal and coronal alignment and significantly improving achievement of goal PI-LL compared with stock devices.

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Global Spine J. 2023 Nov 21:21925682231216926. doi: 10.1177/21925682231216926. Online ahead of print.ABSTRACTSTUDY DESIGN: Multicenter cohort.OBJECTIVES: A report from the International Spine Study Group (ISSG) noted that surgeons failed to achieve alignment goals in nearly two-thirds of 266 complex adult deformity surgery (CADS) cases. We assess whether personalized interbody spacers are associated with improved rates of,

Global Spine J. 2023 Nov 21:21925682231216926. doi: 10.1177/21925682231216926. Online ahead of print.

ABSTRACT

STUDY DESIGN: Multicenter cohort.

OBJECTIVES: A report from the International Spine Study Group (ISSG) noted that surgeons failed to achieve alignment goals in nearly two-thirds of 266 complex adult deformity surgery (CADS) cases. We assess whether personalized interbody spacers are associated with improved rates of achieving goal alignment following adult spinal deformity (ASD) surgery.

METHODS: ASD patients were included if their surgery utilized 3D-printed personalized interbody spacer(s) and they met ISSG CADS inclusion criteria. Planned alignment was personalized by the surgeon during interbody planning. Planned vs achieved alignment was assessed and compared with the ISSG CADS series that used stock interbodies.

RESULTS: For 65 patients with personalized interbodies, 62% were women, mean age was 70.3 years (SD = 8.3), mean instrumented levels was 9.9 (SD = 4.1), and the mean number of personalized interbodies per patient was 2.2 (SD = .8). Segmental alignment was achieved close to plan for levels with personalized interbodies, with mean difference between goal and achieved as follows: intervertebral lordosis = .9° (SD = 5.2°), intervertebral coronal angle = .1° (SD = 4.7°), and posterior disc height = -0.1 mm (SD = 2.3 mm). Achieved pelvic incidence-to-lumbar lordosis mismatch (PI-LL) correlated significantly with goal PI-LL (r = .668, P < .001). Compared with the ISSG CADS cohort, utilization of personalized interbodies resulted in significant improvement in achieving PI-LL <5° of plan (P = .046) and showed a significant reduction in cases with PI-LL >15° of plan (P = .012).

S: This study supports use of personalized interbodies as a means of better achieving goal segmental sagittal and coronal alignment and significantly improving achievement of goal PI-LL compared with stock devices.

PMID:38124314 | DOI:10.1177/21925682231216926

The London Spine Unit : best recognised day surgery hospital in the world

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Analysis of Personalized Interbody Implants in the Surgical Treatment of Adult Spinal Deformity

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Global Spine J. 2023 Nov 21:21925682231216926. doi: 10.1177/21925682231216926. Online ahead of print.ABSTRACTSTUDY DESIGN: Multicenter cohort.OBJECTIVES: A report from the International Spine Study Group (ISSG) noted that surgeons failed to achieve alignment goals in nearly two-thirds of 266 complex adult deformity surgery (CADS) cases. We assess whether personalized interbody spacers are associated with improved rates of
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