Adenoid cystic carcinoma of the larynx in a 70-year-old affected person: A case report.
Oncol Lett. 2018 Sep;16(three):2783-2788
Authors: Ricciardiello F, Addeo R, Di Lullo AM, Abate T, Mazzone S, Oliva F, Motta G, Caraglia M, Mesolella M
Adenoid cystic carcinoma (ACC) is a comparatively uncommon tumor that accounts for <1% of all head and neck malignancies. Laryngeal localization of ACC, which is mostly hypoglottic, is comparatively uncommon, occurring in Zero.07-Zero.25% of all laryngeal tumors. ACC is characterised as a slow-growing tumor with a excessive recurrence charge, which regularly causes dyspnea and hoarseness. ACC displays a propensity for perineural invasion and thus, sufferers could expertise ache as a late symptom of the illness. Distant metastasis happens in 35-50% of instances and the lungs are the commonest website of metastasis. Tumors are normally identified by bodily examination with fiberoscopy and computed tomography of the neck and chest, as a result of excessive charge of lung metastases. The usual remedy for ACC is surgical procedure adopted by radiotherapy. On this research, a 70-year-old affected person offered with laryngeal ACC, who underwent whole laryngectomy with bilateral neck dissection and adjuvant radiotherapy, is offered. Comply with-up examination carried out 2 years after surgical procedure revealed no proof of locoregional recurrence or distant metastases. Beforehand printed literature relating to ACC of the larynx was additionally reviewed.
PMID: 30127863 [PubMed]