Acupuncture for musculoskeletal ache: A meta-analysis and meta-regression of sham-controlled randomized scientific trials.
Sci Rep. 2016 07 29;6:30675
Authors: Yuan QL, Wang P, Liu L, Solar F, Cai YS, Wu WT, Ye ML, Ma JT, Xu BB, Zhang YG
The goals of this systematic evaluate have been to check the analgesic impact of actual acupuncture and to discover whether or not sham acupuncture (SA) kind is said to the estimated impact of actual acupuncture for musculoskeletal ache. 5 databases have been searched. The result was ache or incapacity instantly (?1 week) following an intervention. Standardized imply variations (SMDs) with 95% confidence intervals have been calculated. Meta-regression was used to discover doable sources of heterogeneity. Sixty-three research (6382 people) have been included. Eight situation varieties have been included. The pooled impact measurement was reasonable for ache aid (59 trials, 4980 people, SMD -Zero.61, 95% CI -Zero.76 to -Zero.47; P?<?Zero.001) and enormous for incapacity enchancment (31 trials, 4876 people, -Zero.77, -1.05 to -Zero.49; P?<?Zero.001). In a univariate meta-regression mannequin, sham needle location and/or depth might clarify most or all heterogeneities for some situations (e.g., shoulder ache, low again ache, osteoarthritis, myofascial ache, and fibromyalgia); nevertheless, the interactions between subgroups through these covariates weren’t important (P?<?Zero.05). Our evaluate supplied low-quality proof that actual acupuncture has a reasonable impact (approximate 12-point discount on the 100-mm visible analogue scale) on musculoskeletal ache. SA kind didn’t look like associated to the estimated impact of actual acupuncture.
PMID: 27471137 [PubMed – indexed for MEDLINE]