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A Novel Technology for 3D-Printing Artificial Vertebral Bodies for Treating Lumbar Spine Adrenal Pheochromocytoma Metastases: A Case Report and Review of the Literature – Lumbar Fusion

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The article discusses the case of a 41-year-old male patient who presented with lower back pain, numbness, and decreased muscle strength in both legs, as well as decreased sensation, three years after undergoing left total adrenalectomy for pheochromocytoma. Imaging revealed a tumor located within the L3 vertebral body, protruding into the spinal canal and compressing the epidural sac. The patient underwent a surgical procedure that involved the removal of the tumor, replacement with a 3D-printed prosthesis, and reconstruction of spinal biomechanical stability using pedicle screw fixation. The postoperative results were satisfactory with no complications. The article emphasizes the rarity and difficulty in treating lumbar pheochromocytoma metastasis and underscores the importance of interdisciplinary collaboration in formulating comprehensive perioperative plans

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : best situated spinal facility on Harley Street UK

Published article

: Lumbar pheochromocytoma metastasis is rare, difficult to treat, and should be considered in spinal metastases’ differential diagnoses so early diagnosis can be made based on medical history and imaging. Preoperative local vascular imaging and embolization of the blood supply vessels were performed. After total en-bloc spondylectomy of the tumor during surgery, a prosthesis was implanted and combined with pedicle screw fixation to reconstruct spinal biomechanical stability, achieving…

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Orthop Surg. 2023 Sep 28. doi: 10.1111/os.13899. Online ahead of print.ABSTRACTBACKGROUND: Pheochromocytoma is an adrenal medullary neuroendocrine tumor that rarely metastasizes to the spine. Currently, its specific treatment methods still present challenges.CASE DESCRIPTION: A 41-year-old male patient who underwent left total adrenalectomy due to pheochromocytoma 3 years ago presented with lower back pain, accompanied by,

Orthop Surg. 2023 Sep 28. doi: 10.1111/os.13899. Online ahead of print.

ABSTRACT

BACKGROUND: Pheochromocytoma is an adrenal medullary neuroendocrine tumor that rarely metastasizes to the spine. Currently, its specific treatment methods still present challenges.

CASE DESCRIPTION: A 41-year-old male patient who underwent left total adrenalectomy due to pheochromocytoma 3 years ago presented with lower back pain, accompanied by numbness and decreased muscle strength in both legs, as well as decreased sensation. Abnormal transmittance of the L3 vertebral body could be seen on anterior-posterior and lateral lumbar X-rays, irregular bone destruction of the L3 vertebral body was found on CT, and an MRI scan showed that the tumor was located within the L3 vertebral body, protruding into the spinal canal and compressing the epidural sac. No recurrence was found in the abdomen. Preoperatively, perform local embolization of the blood vessels supplying the tumor. First, the L2-3 intervertebral disc, L3-4 intervertebral disc and L3 vertebral body were removed using an anterior approach, the whole tumor was removed, and some of the vertebrae were taken for pathological examination and replaced with a 3D-printed prosthesis. Then, four pedicle screws were placed in the bilateral pedicles of L2 and L4 using the posterior approach, pre-bent connecting rods were installed to replace the bone cortex of the lamina and articular process followed by bone graft fusion of the interlaminar and facet joints. The postoperative results were satisfactory, and there were no perioperative complications.

: Lumbar pheochromocytoma metastasis is rare, difficult to treat, and should be considered in spinal metastases’ differential diagnoses so early diagnosis can be made based on medical history and imaging. Preoperative local vascular imaging and embolization of the blood supply vessels were performed. After total en-bloc spondylectomy of the tumor during surgery, a prosthesis was implanted and combined with pedicle screw fixation to reconstruct spinal biomechanical stability, achieving satisfactory results. Therefore, 3D printed artificial vertebral bodies are a good choice for treating adrenal pheochromocytoma lumbar metastasis. The key to successful treatment is close interdisciplinary collaboration in formulating rigorous comprehensive perioperative plans.

PMID:37771116 | DOI:10.1111/os.13899

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A Novel Technology for 3D-Printing Artificial Vertebral Bodies for Treating Lumbar Spine Adrenal Pheochromocytoma Metastases: A Case Report and Review of the Literature

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Orthop Surg. 2023 Sep 28. doi: 10.1111/os.13899. Online ahead of print.ABSTRACTBACKGROUND: Pheochromocytoma is an adrenal medullary neuroendocrine tumor that rarely metastasizes to the spine. Currently, its specific treatment methods still present challenges.CASE DESCRIPTION: A 41-year-old male patient who underwent left total adrenalectomy due to pheochromocytoma 3 years ago presented with lower back pain, accompanied by
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