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[A Case of Skull Base Metastasis of Breast Cancer with Dysphasia, Odynophagia and Dysarthria].
Gan To Kagaku Ryoho. 2017 Nov;44(12):1343-1345
Authors: Takahashi H, Uno M, Miyoshi Okay
Summary
Whereas cranium base metastases from breast most cancers will not be unusual, there are comparatively few reported circumstances within the literature. We report a case of cranium base metastasis of breast most cancers that resulted in dysphasia, odynophagia, and dysarthria. The case concerned a girl in her 50 s who was recognized with most cancers of the best breast(cT4N1M0, cStage III B)at one other medical establishment 9 years beforehand and who underwent a partial mastectomy and an axillary lymph node dissection following neoadjuvant chemotherapy. She started experiencing neck ache 6 months beforehand, adopted by dysphasia, odynophagia, and dysarthria 1 month beforehand. The affected person was referred to our hospital for detailed examination and therapy. PET-CT and cranial MRI was performed and detected metastatic lesion from the cranium base to the higher cervical vertebrae. An orthopedic surgeon carried out a posterior decompression and fusion surgical procedure on the occipital bone, cervical vertebra, and thoracic vertebra. A histological examination of bone tissue extracted throughout surgical procedure revealed that the breast most cancers had metastasized. We then carried out irradiation of the cervical vertebra from the cranial base and initiated therapy with zoledronic acid and anastrozole. Signs comparable to dysphasia, odynophagia and dysarthria lessened, and the affected person is presently being followedupas an outpatient.
PMID: 29394628 [PubMed – in process]