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A Case of Holocord Leptomeningeal Dissemination from Cerebellar Hemangioblastoma with out von Hippel-Lindau Illness.

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A Case of Holocord Leptomeningeal Dissemination from Cerebellar Hemangioblastoma with out von Hippel-Lindau Illness.

Hiroshima J Med Sci. 2017 Mar;66(1):7-10

Authors: Ohba H, Yamaguchi S, Magaki T, Takeda M, Kolakshyapati M, Sadatomo T, Kurisu Ok

Summary
Hemangioblastoma disseminated alongside leptomeninges from the solitary cranial lesion with out von Hippel-Lindau (VHL) illness is a fairly uncommon occasion with 23 instances reported in 40 years. We add a brand new case and focus on these uncommon cases. A 55-year-old feminine underwent surgical procedure for whole elimination of cerebellar hemangioblastoma. Twenty months later, magnetic resonance (MR) photographs of the spinal twine revealed a tumor compressing the thoracic twine at T3-Four degree which was eliminated en bloc by emergent spinal surgical procedure. Nevertheless, paraplegia and bowel bladder dysfunction recurred 5 months after the spinal surgical procedure. Backbone MR photographs confirmed diffuse enhancement of subarachnoid house. Exploratory surgical procedure disclosed that the improved lesion was disseminated hemangioblastoma. After complete spinal irradiation, she was transferred to a palliative care hospital. Even after full elimination, chance of leptomeningeal dissemination calls for steady follow-up. The mechanism of seeding of hemangioblastoma stays unclear, however consideration should be paid to keep away from spreading tumor cells throughout surgical procedure as a result of all of the disseminated instances had precedent cranial surgical procedure.

PMID: 29986122 [PubMed – indexed for MEDLINE]

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