A Case of Autosplenectomy in Sickle Cell Trait Following an Publicity to Excessive Altitude.
Wilderness Environ Med. 2018 03;29(1):85-89
Authors: Yanamandra U, Das R, Malhotra P, Varma S
A 24-year-old man offered with acute stomach ache upon ascent to reasonable altitude (3500 m). A direct analysis revealed a splenic infarct, and he was evacuated to sea stage. Upon restoration, he was despatched again to 3500 m with out detailed etiological analysis, whereupon he skilled recurrent episodes of left-side subcostal ache. Imaging recommended autosplenectomy, and workup revealed a unfavorable thrombophilia profile however was constructive for sickle cell trait (SCT). People with SCT will be asymptomatic till publicity to extreme hypoxia, upon which they’ll manifest clinically as sickle cell syndrome. We focus on the uncommon presentation of autosplenectomy in a affected person with beforehand undiagnosed SCT on publicity to excessive altitude.
PMID: 29331296 [PubMed – indexed for MEDLINE]