5-Aminolevulinic acid fluorescence-guided surgical procedure for spinal twine melanoma metastasis: a technical notice.
Acta Neurochir (Wien). 2018 Aug 09;:
Authors: Ruschel LG, Ramina R, da Silva EB, Cavalcanti MS, Duarte JFS
BACKGROUND: Based on our analysis, simply few research described 5-Aminolevulinic acid (5-ALA) use for spinal accidents resection. 5-ALA is understood to be particularly helpful in sure spinal tumor entities resembling meningiomas, ependymomas, hemangiopericytomas, and metastasis of central nervous system main tumors. In distinction, 5-ALA has restricted worth in different histopathological tumoral entities, as neurinomas and carcinoma metastasis.
METHOD: We describe a microsurgical resection of a spinal twine melanoma by way of fluorescence-guided approach utilizing 5-ALA in a 36-year-old man.
RESULTS: Robust 5-ALA tumor enhancement was evidenced, leading to gross-total resection.
CONCLUSION: To our data, that is the primary case of nonglial intramedullary metastasis with 5-ALA constructive staining. We consider that this software, 5-ALA, may assist within the resection, identification, and differentiation of medullary metastasis.
PMID: 30091052 [PubMed – as supplied by publisher]