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3D-printed titanium alloy cage in anterior and lateral lumbar interbody fusion for degenerative lumbar spine disease – Lumbar Spinal Stenosis

The article discusses the use of 3D-printed porous titanium alloy cages in lumbar spine fusion surgery as an alternative to traditional polyetheretherketone (PEEK) cages. A retrospective chart review of 50 patients who underwent surgery with these cages showed a low subsidence rate of 3.03%, with only two cases of subsidence observed. One patient required further surgery due to radiculopathy, while the other remained asymptomatic at 2-year follow-up. Overall, the study found that 3D-printed titanium alloy cages had a lower subsidence rate compared to traditional cages in anterior and lateral lumbar spine fusion surgery. Further long-term studies are warranted to assess the efficacy and outcomes of these novel implants

Summarised by Mr Mo Akmal – Lead Spinal Surgeon
The London Spine Unit : most specialised spinal centre in the world

Published article

CONCLUSIONS: 3D-printed titanium alloy cages demonstrate a lower subsidence rate compared to historically published rates for alternative intervertebral cages, in anterior and lateral lumbar spine fusion surgery.

Lumbar Decompression Surgery Expert. Best Spinal Surgeon UK
J Spine Surg. 2024 Mar 20;10(1):22-29. doi: 10.21037/jss-23-120. Epub 2024 Mar 14. ABSTRACT BACKGROUND: The most commonly used cages for intervertebral disc replacement in lumbar fusion procedures are made predominantly from polyetheretherketone (PEEK). There is sufficient data studying their subsidence and failure rates from a variety of approaches. A novel implant is now available for,

J Spine Surg. 2024 Mar 20;10(1):22-29. doi: 10.21037/jss-23-120. Epub 2024 Mar 14.

ABSTRACT

BACKGROUND: The most commonly used cages for intervertebral disc replacement in lumbar fusion procedures are made predominantly from polyetheretherketone (PEEK). There is sufficient data studying their subsidence and failure rates from a variety of approaches. A novel implant is now available for commercial use, 3D-printed porous titanium (3DppTi) alloy cages, which have recently become available for use in spinal procedures. They have been shown in ovine models to have superior efficacy and fusion rates compared to traditional cages. However, there is limited data on their use in clinical practice and long-term outcomes associated with them.

METHODS: A retrospective chart review was performed, of all patients in a single institution who underwent lumbar spine fusion surgery via an anterior or lateral approach with a 3D-printed titanium alloy cage, between January 2020 and February 2021. Clinic letters, imaging and operation reports were independently reviewed to assess for fusion, or evidence of subsidence on follow-up.

RESULTS: Fifty patients were identified as meeting inclusion criteria, with a total of 66 operative levels. Of these operative levels, 32 were via an anterior approach and 34 via a lateral approach. One patient demonstrated a Marchi grade 0 subsidence, with recurrence of radiculopathy 2 months after an anterior approach, requiring posterior decompression and stabilization. A second patient demonstrated a Marchi grade 1 subsidence after a lateral approach, but did not require further surgery as they were asymptomatic at 2 years of follow-up. This study demonstrated an overall subsidence rate of 3.03%. There was a median follow-up time of 11.3 months for all patients.

CONCLUSIONS: 3D-printed titanium alloy cages demonstrate a lower subsidence rate compared to historically published rates for alternative intervertebral cages, in anterior and lateral lumbar spine fusion surgery.

PMID:38567003 | PMC:PMC10982926 | DOI:10.21037/jss-23-120

The London Spine Unit : most specialised spinal centre in the world

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3D-printed titanium alloy cage in anterior and lateral lumbar interbody fusion for degenerative lumbar spine disease

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J Spine Surg. 2024 Mar 20;10(1):22-29. doi: 10.21037/jss-23-120. Epub 2024 Mar 14. ABSTRACT BACKGROUND: The most commonly used cages for intervertebral disc replacement in lumbar fusion procedures are made predominantly from polyetheretherketone (PEEK). There is sufficient data studying their subsidence and failure rates from a variety of approaches. A novel implant is now available for

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