151 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: laminectomy These pubmed results were generated on 2012/06/23 PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950’s. These citations are from MEDLINE…

146 new pubmed citations were retrieved for your search.
Click on the search hyperlink below to display the complete search results:


These pubmed results were generated on 2012/03/10

PubMed, a service of the National Library of Medicine, includes over 15 million
citations for biomedical articles back to the 1950’s.
These citations are from MEDLINE and additional life science journals.
PubMed includes links to many sites providing full text articles and other related resources.

Spontaneous C1 anterior arch fracture as a postoperative complication of foramen magnum decompression for Chiari malformation type 1.

Surg Neurol Int. 2011;2:138

Authors: Hirano Y, Sugawara A, Mizuno J, Takeda M, Watanabe K, Ogasawara K

BACKGROUND: C1 fracture accounts for 2% of all spinal column injuries and 10% of cervical spine fractures, and is most frequently caused by motor vehicle accidents and falls. We present a rare case of C1 anterior arch fracture following standard foramen magnum decompression for Chiari malformation type 1.
CASE DESCRIPTION: A 63-year-old man underwent standard foramen magnum decompression (suboccipital craniectomy and C1 laminectomy) under a diagnosis of Chiari malformation type 1 with syringomyelia in June 2009. The postoperative course was uneventful until the patient noticed progressive posterior cervical pain 5 months after the operation. Computed tomography of the upper cervical spine obtained 7 months after the operation revealed left C1 anterior arch fracture. The patient was referred to our hospital at the end of January 2010 and C1-C2 posterior fusion with C1 lateral mass screws and C2 laminar screws was carried out in March 2010. Complete pain relief was achieved immediately after the second operation, and the patient resumed his daily activities.
CONCLUSION: Anterior atlas fracture following foramen magnum decompression for Chiari malformation type 1 is very rare, but C1 laminectomy carries the risk of anterior arch fracture. Neurosurgeons should recognize that fracture of the atlas, which commonly results from an axial loading force, can occur in the postoperative period in patients with Chiari malformation.

PMID: 22059133 [PubMed]

Retrograde C0-C1 insertion of cervical plate electrode for chronic intractable neck and arm pain.

World Neurosurg. 2011 Sep-Oct;76(3-4):352-4; discussion 268-9

Authors: Moens M, De Smedt A, Brouns R, Spapen H, Droogmans S, Duerinck J, D’Haese J, D’Haens J, Nuttin B

OBJECTIVE: Spinal cord stimulation is an effective treatment for chronic neuropathic pain after spinal surgery. In addition to the most common placement of electrodes at the thoracic level for low back and leg pain, electrodes can also be placed on a cervical level in patients with chronic neck and upper limb pain. Surgical insertion of plate electrodes via an orthodromal direction requires a partial laminectomy. Therefore, the authors describe a surgical technique using retrograde insertion of a plate electrode to avoid laminectomy.
METHODS: Six patients with uncontrolled neck and upper limb pain despite optimal analgesic medication were treated with a surgical electrode placed at the C1-C2 level via a retrograde placement technique without laminectomy.
RESULTS: All patients received stimulation paresthesias at the desired regions and reported significant pain reduction in the neck and arm regions.
CONCLUSION: This retrograde placement of plate electrodes enables cervical lordosis to be overcome and results in adequate stimulation of the upper cervical region, which is mandatory to reduce neck and shoulder pain without laminectomy.

PMID: 21986436 [PubMed – in process]

Fibromatosis of the Cervical Region Following Laminectomy: A Case Report and Literature Review.

Spine (Phila Pa 1976). 2011 Sep 8;

Authors: Sevak S, Blount AL, Cottingham S, Delano M, Woude DL, Stevenson J, Chung MH

STRUCTURED ABSTRACT AND KEY WORDS: Study Design. A case report and a discussion of recent published data.Objective. To highlight the occurrence of post-operative fibromatosis arising in the cervical spine.Summary of Background Data. Fibromatosis is a benign, locally invasive fibroblastic proliferation that can cause compressive effects on adjacent structures. Although the precise etiology of fibromatosis remains unclear, numerous studies have investigated the role of pluripotent mesenchymal stem cells in beta-catenin regulated tumorigenesis. At present, aggressive fibromatosis is managed with wide local excision. Postoperative radiation therapy is indicated for incomplete excision.Methods. A 48-year-old woman presented with a two-year history of enlarging paracervical fibromatosis after undergoing extensive cervicothoracic instrumentation for excision of an extradural schwannoma. The patient underwent wide local excision of the neck mass with right trapezius myocutaneous flap reconstruction of the subsequent defect.Results. Histologically, the lesion was shown to be fibromatosis. Six months post-operatively the patient is doing well with no recurrence.Conclusion. Fibromatosis is an important diagnosis to consider when evaluating locally aggressive spinal lesions at sites of prior operative repair. Molecular and genetic studies pertaining to the role of mesenchymal stem cells and beta-catenin in the pathogenesis of aggressive fibromatosis tumors could lead to possible worthwhile treatment strategies in the future.

PMID: 21912314 [PubMed – as supplied by publisher]

Effect of topical application of mitomycin-C on wound healing in a postlaminectomy rat model: An experimental study.

Eur J Pharmacol. 2011 Oct 26;

Authors: Su C, Sui T, Zhang X, Zhang H, Cao X

The aim of this study was to investigate the effects of topical application mitomycin-C (MMC) on wound healing after laminectomy. 60 adult male SD rats were equally and randomly divided into five groups. Laminectomy was performed at the level of L1 in all rats. After hemostasis was achieved, cotton pads soaked with saline and MMC (0.1mg/ml, 0.3mg/ml, 0.5mg/ml and 0.7mg/ml) were directly subjected to the exposed dura for 5min in each group. Two weeks after laminectomy all the rats were killed. The vertebral column including the back scar tissue and muscles was obtained to make paraffin sections. The hematoxylin-eosin staining and Masson staining were performed with the obtained paraffin sections. The number of the fibroblast and the capillary density were counted by the hematoxylin-eosin staining slice. The extent of epidural fibrosis and the expression of vascular endothelial growth factor (VEGF) were evaluated by the immunohistochemical slice through a computer image analysis system. Our data showed that the number of fibroblast, capillary density and fibrotic tissue in the 0.5 and 0.7mg/ml MMC groups was significantly lower than the control, 0.1 and 0.3mg/ml MMC groups; while the expression of VEGF in control and 0.1mg/ml MMC groups was notably higher than 0.3, 0.5 and 0.7mg/ml MMC groups. Topical application of MMC above the concentration of 0.3mg/ml could affect all steps of the wound healing process via inhibiting the angiogenesis and fibroblast proliferation, thus delayed the wound healing after laminectomy.

PMID: 22056834 [PubMed – as supplied by publisher]

Surgical decompression of a caudal vertebral disc extrusion by dorsal laminectomy.

Vet Comp Orthop Traumatol. 2011 Oct 6;25(1)

Authors: Potanas CP, Grange A, Casale SA

A 3.5-year-old female spayed Beagle cross was presented to our emergency and referral facility for the complaint of acute onset paralysis of the tail. A full physical and neurological examination was performed which confirmed the absence of motor function in the tail. Signs of superficial and deep pain sensation to the tail remained intact. Orthogonal view survey radiographs identified mineralization superimposed over the intervertebral foramen of the first and second caudal vertebrae. A dorsal laminectomy was performed for surgical decompression of the caudal nerve roots. On the fourth postoperative day, the patient exhibited good motor function of the tail. Neurological improvement continued and 11 days postoperatively the patient demonstrated normal neurological function, free range-of-motion of the tail, and it did not exhibit any signs of pain. Follow-up examination was performed 76 days after surgery, at which time the patient exhibited normal neurological function and signs of a pain-free range-of-motion on manipulation of its tail.

PMID: 21976157 [PubMed – as supplied by publisher]

Long-duration perforated patch recordings from spinal interneurons of adult mice.

J Neurophysiol. 2011 Nov;106(5):2783-9

Authors: Husch A, Cramer N, Harris-Warrick RM

It has been very difficult to record from interneurons in acute slices of the lumbar spinal cord from mice >3 wk of age. The low success rate and short recording times limit in vitro experimentation on mouse spinal networks to neonatal and early postnatal periods when locomotor networks are still developmentally immature. To overcome this limitation and enable investigation of mature locomotor network neurons, we have established a reliable procedure to record from spinal cord neurons in slices from adult, behaviorally mature mice of any age. Two key changes to the established neonate procedure were implemented. First, we remove the cord by a dorsal laminectomy from a deeply anesthetized animal. This enables respiration and other vital functions to continue up to the moment the maximally oxygenated lumbar spinal cord is removed, improving the health of the slices. Second, since adult spinal cord interneurons appear more sensitive to the intracellular dialysis that occurs during whole cell recordings, we introduced perforated patch recordings to the procedure. Stable recordings up to 12 h in duration were obtained with our new method. This will allow investigation of changes in mature neuronal properties in disease states or after spinal cord injury and allow prolonged recordings of responses to drug application that were previously impossible.

PMID: 21900514 [PubMed – in process]

Management of symptomatic intrathecal catheter-associated inflammatory masses.

Clin Neurol Neurosurg. 2011 Nov 4;

Authors: Tomycz ND, Ortiz V, McFadden KA, Urgo L, Moossy JJ

OBJECTIVE: Intrathecal catheter-associated inflammatory masses (CIMs) are a serious complication of implanted drug pumps. The goal of this study was to review our experience with CIMs, including the pathology of all resected CIMs, and identify objective data which may guide management. METHODS: We performed a retrospective review of 13 patients who developed symptomatic CIMs during continuous intrathecal opioid therapy for chronic pain. Eight patients presented with pain plus neurologic deficit and 5 patients presented with pain alone. RESULTS: CIM resection via laminectomy and intradural exploration was ultimately performed in 8 patients, 3 of whom were initially treated with a non-resective surgical approach (catheter repositioning or pump removal) that failed. All 3 patients who experienced a failure with non-resective surgery had CIMs located in the thoracic spine with a maximum diameter?13mm and 2 of these patients had neurologic deficits on presentation. CONCLUSIONS: Our experience, with the largest reported single-surgeon series of patients harboring CIMs, favors early resection, especially in patients with neurologic deficit. Resection may also be a prudent first-line strategy for patients with larger thoracic masses (?13mm) regardless of neurologic status. Neurologic deficits engendered by CIM usually improve after resection and the majority of patients in our series would have still elected to have an intrathecal pump for pain control knowing a CIM would have developed.

PMID: 22056761 [PubMed – as supplied by publisher]

[Treatment of spontaneous spinal epidural hematoma].

No Shinkei Geka. 2011 Oct;39(10):947-52

Authors: Kokubo R, Kim K, Sugawara A, Nomura R, Morimoto D, Isu T, Kobayashi S, Teramoto A

Objective: Spontaneous spinal epidural hematoma (SSEH) is rare. There was not enough information about diagnosis and treatment of SSEH, although they require emergency surgery and some surgeons may hesitate to use alternative treatments. We report our six cases SSEH and discuss treatment of SSEH from the literature. Materials and Methods: We encountered six cases of SSEH. They were 4 female and 2 male cases and age ranged from 61 to 75 years (averaging 67.3 years). The SSEH were located in the cervical (n=3), cervicothoracic (n=3) regions. In 4 cases, there were hematomas at the right side of the spinal epidural space, and 2 cases were at the left side. Results: All cases experienced severe neck or shoulder pain. In five cases, hemiparesis was noted. Cervical MRI showed that epidural hematoma had compressed the spinal cord posterolateraly. In all cases, cervical CT scans also revealed epidural hematoma, too. Five cases were operated on by removal of the hematoma with hemilaminectomy and one case was operated on with laminectomy because of severe paresis. The mean time since the start of the operation was 11 hours (ranging from 7 to 20 hours). Only one case who had only severe pain without paresis was treated conservatively. All except two patients completely recovered neurologically. The two cases continued to have sensory disturbance. Conclusions: We successfully treated 6 cases of SSEH. MRI is useful for diagnosis of SSEH, and CT scan can also diagnose it as in our cases. Cases with severe neurological deficit would be considered as needing surgical treatment at an appropriate time and the cases without neurological deficit should be kept under observation until surgery becomes necessary.

PMID: 21972183 [PubMed – in process]

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